CytoSelect™ 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

These cell transformation assays are designed and optimized for 96-well plates, but can easily be adapted for use in 48, 24, 12 or 6-well plates. Both colorimetric and fluorometric formats are available.

1. Hirata, H. et al. (2010). Role of secreted Frizzled-related protein3 in human renal cell carcinoma. Cancer Res. 70:1896-1905 (#CBA-135).
2. Xie, G. et al. (2009). Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells. Am. J. Physiol. Gastrointest. Liver Physiol. 296:G755-G763 (#CBA-135).
3. Hirata, H. et al. (2009). Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways. Clin. Cancer Res. 15:5678-5687 (#CBA-135).
4. Ke, X-S. et al. (2008). Epithelial to mesenchymal transition of a primary prostate cell line with switches of cell adhesion modules but without malignant transformation. PLoS One 3(10):e3368 (#CBA-135).