Adenovirus Transduction

  • Increases transduction efficiency of adenovirus up to 12-fold in cells expressing little or no CAR (coxsackievirus-adenovirus receptor)
  • May also increase efficiency in some CAR-expressing cells
  • Requires only a short incubation prior to infection

 

Frequently Asked Questions about Adenovirus Purification

General FAQs about using Adenovirus

General FAQs about Viral Gene Delivery

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ViraDuctin™ Adenovirus Transduction Reagent
Catalog Number
AD-200
Size
10 transductions
Detection
N/A
Manual/Data Sheet Download
SDS Download
Price
$315.00
ViraDuctin™ Adenovirus Transduction Reagent
Catalog Number
AD-201
Size
50 transductions
Detection
N/A
Manual/Data Sheet Download
SDS Download
Price
$775.00
Product Details

Adenoviral infection of most cells is mediated largely by the coxsackievirus-adenovirus receptor (CAR). In many cells, however, this receptor is either absent or present at extremely low levels, reducing the efficiency of adenovirus uptake.

ViraDuctin™ Adenovirus Transduction Reagent is designed specifically to increase the efficiency of adenoviral transduction without regard to the level of CAR expression on the surface of the target cells.

*Note: The number of transductions per vial is based on the use of 6-well plates or 35 mm culture dishes. However, this product may also be used with 96-well, 24-well or 12-well plates, as well as 60 mm or 100 mm dishes. See product manual for details.

Enhanced Transduction using the ViraDuctin™ Adenovirus Transduction Reagent. Infection of NIH3T3 cells with recombinant ß-gal Recombinant Adenovirus (#ADV-002). X-gal staining under microscope.

Enhanced Transduction using the ViraDuctin™ Adenovirus Transduction Reagent. Infection of NIH3T3 cells with recombinant ß-gal Recombinant Adenovirus (#ADV-002). Scoring of infection with ViraDuctin™ reagent as a percentage of infection compared to control.

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