Human Epididymis Protein 4 (HE4) is a relatively new tumor marker. The product of the WFDC2 gene, HE4 is often overexpressed in patients with ovarian carcinoma. Elevated levels of HE4 have been demonstrated in early stages of tumor progression, even in patients with normal levels of CA 125, and appears to have higher specificity than CA 125. Determining serum levels of both HE4 and CA 125 biomarkers is potentially valuable for monitoring ovarian cancer.
Our HE4 ELISA Kit measures the levels of human epididymis protein 4 in serum or plasma samples as well as in cell lysates.