Leukocyte or tumor cell interactions with vascular endothelium consist of a cascade of processes including the firm attachment of cells to endothelial cell adhesion molecules.
The CytoSelect™ Leukocyte Epithelium Adhesion Assay provides a robust system for the quantitative determination of interactions between leukocytes and epithelium. Adherent cells can be easily quantified on a fluorescence plate reader.
Schweitzer, K.S. et al. (2020). IGSF3 mutation identified in patient with severe COPD alters cell function and motility. JCI Insight. doi: 10.1172/jci.insight.138101.