Nitrotyrosine Immunoblot Kit

Nitrotyrosine Immunoblot Kit
  • Detect 3-Nitrotyrosine formation by Western blot
  • Suitable for use with cell lysates, serum, plasma and purified proteins
Email To BuyerPrint this PageCopy Link
Ordering

Please contact your distributor for pricing.

OxiSelect™ Nitrotyrosine Protein Immunoblot Kit
Catalog Number
STA-303
Size
10 blots
Detection
Immunoblot
Manual/Data Sheet Download
SDS Download
Price
$315.00
Product Details

Nitric oxide influences a variety of biological processes including cell proliferation, apoptosis, neurotoxicity and extracellular matrix remodeling. Nitric oxide reacts with superoxide to form peroxynitrite, which in turn nitrates tyrosine residues in proteins. Nitrotyrosine therefore serves as a marker for peroxynitrite action in a variety of disease states and in conditions of cellular damage and oxidative stress.

Our OxiSelect™ Nitrotyrosine Immunoblot Kit provides a simple method to measure the formation of 3-nitrotyrosine in proteins by Western blot detection.

Formation of 3-Nitrotyrosine During Oxidative Stress. An increase in the presence of nitrotyrosine is correlated with an increase in the presence of nitric oxide (NO).

Recent Product Citations
  1. Annunziata, G. et al. (2020). Grape Polyphenols Ameliorate Muscle Decline Reducing Oxidative Stress and Oxidative Damage in Aged Rats. Nutrients. 12(5). pii: E1280. doi: 10.3390/nu12051280.
  2. Capó, X. et al. (2020). Calorie Restriction Improves Physical Performance and Modulates the Antioxidant and Inflammatory Responses to Acute Exercise. Nutrients. 12:930. doi: 10.3390/nu12040930.
  3. Kondo, T. et al. (2019). Prebiotic effect of fructooligosaccharides on the inner ear of DBA/2 J mice with early-onset progressive hearing loss. J Nutr Biochem. doi: 10.1016/j.jnutbio.2019.108247.
  4. Sureda, A. et al. (2016). Mediterranean diets supplemented with virgin olive oil and nuts enhance plasmatic antioxidant capabilities and decrease xanthine oxidase activity in people with metabolic syndrome: The PREDIMED study. Mol Nutr Food Res. doi:10.1002/mnfr.201600450.
  5. Shivanna, B. et al. (2015). Omeprazole attenuates pulmonary aryl hydrocarbon receptor activation and potentiates hyperoxia-induced developmental lung injury in newborn mice. Toxicol Sci. doi:10.1093/toxsci/kfv183.
  6. Capó, X. et al. (2015). Diet supplementation with DHA-enriched food in football players during training season enhances the mitochondrial antioxidant capabilities in blood mononuclear cells. Eur J Nutr. 54:35-49.
  7. Martorell, M. et al. (2014). Docosahexaenoic acid supplementation promotes erythrocyte antioxidant defense and reduces protein nitrosative damage in male athletes. Lipids. 50:131-148.
  8. Sakellariou, G. K. et al. (2014). Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice. FASEB J.  28:1666-1681.