AAV CMV Expression Vector

AAV CMV Expression Vector
  • Cloning capacity = 3 kb

 

Frequently Asked Questions about AAV Expression and Packaging

General FAQs about using AAV

General FAQs about Viral Gene Delivery

Email To BuyerPrint this PageCopy Link
Ordering

Please contact your distributor for pricing.

pAAV-MCS Expression Vector
Catalog Number
VPK-410
Size
10 µg
Detection
N/A
Manual/Data Sheet Download
SDS Download
Map Download
Sequence Download
Price
$555.00
Product Details

Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

Recent Product Citations
  1. Liu, P.Y. et al. (2023). RNF128 regulates neutrophil infiltration and myeloperoxidase functions to prevent acute lung injury. Cell Death Dis. 14(6):369. doi: 10.1038/s41419-023-05890-1.
  2. Yan, H. et al. (2022). MDMX elevation by a novel Mdmx-p53 interaction inhibitor mitigates neuronal damage after ischemic stroke. Sci Rep. 12(1):21110. doi: 10.1038/s41598-022-25427-4.
  3. Seo, J. et al. (2022). Myristoylation-dependent palmitoylation of cyclin Y modulates long-term potentiation and spatial learning. Prog Neurobiol. doi: 10.1016/j.pneurobio.2022.102349.
  4. Tricaud, N. et al. (2022). Traumatic and Diabetic Schwann Cell Demyelination Is Triggered by a Transient Mitochondrial Calcium Release through Voltage Dependent Anion Channel 1. Biomedicines. 10(6):1447. doi: 10.3390/biomedicines10061447.
  5. Boyer, J.G. et al. (2022). Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy. Nat Commun. 13(1):2940. doi: 10.1038/s41467-022-30619-7.
  6. Kashihara, T. et al. (2022). YAP mediates compensatory cardiac hypertrophy through aerobic glycolysis in response to pressure overload. J Clin Invest. doi: 10.1172/JCI150595.
  7. Huang, C. et al. (2021). TBN improves motor function and prolongs survival in a TDP-43M337V mouse model of ALS. Hum Mol Genet. doi: 10.1093/hmg/ddab101.
  8. Zubkova, E.S. et al. (2021). Transduction of rat and human adipose-tissue derived mesenchymal stromal cells by adeno-associated viral vector serotype DJ. Biol Open. doi: 10.1242/bio.058461.
  9. Vanhoutte, D. et al. (2021). Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy. Nat Commun. 12(1):3928. doi: 10.1038/s41467-021-24215-4.
  10. Asahina, M. et al. (2021). Reversibility of motor dysfunction in the rat model of NGLY1 deficiency. Mol Brain. 14(1):91. doi: 10.1186/s13041-021-00806-6.
  11. Liu, P.Y. et al. (2021). E3 ubiquitin ligase Grail promotes hepatic steatosis through Sirt1 inhibition. Cell Death Dis. 12(4):323. doi: 10.1038/s41419-021-03608-9.
  12. Bai, M. et al. (2020). Critical regulation of a NDIME/MEF2C axis in embryonic stem cell neural differentiation and autism. EMBO Rep. doi: 10.15252/embr.202050283.
  13. Silva-Pilipich, N. et al. (2020). Long-Term Systemic Expression of a Novel PD-1 Blocking Nanobody from an AAV Vector Provides Antitumor Activity without Toxicity. Biomedicines. 8(12):E562. doi: 10.3390/biomedicines8120562.
  14. Zhu, J. et al. (2020). Preparation of a Bacteriophage T4-based Prokaryotic-eukaryotic Hybrid Viral Vector for Delivery of Large Cargos of Genes and Proteins into Human Cells. Bio-protocol. 10(07): e3573. doi: 10.21769/BioProtoc.3573.
  15. Deng, X. et al. (2020). Establishment of a Recombinant AAV2/HBoV1 Vector Production System in Insect Cells. Genes (Basel). 11(4). pii: E439. doi: 10.3390/genes11040439.
  16. Jang, M. et al. (2018). Adeno-Associated Viral Vector Serotype DJ-Mediated Overexpression of N171-82Q-Mutant Huntingtin in the Striatum of Juvenile Mice Is a New Model for Huntington's Disease. Front Cell Neurosci. 12:157. doi: 10.3389/fncel.2018.00157.
  17. Hoshino, Y. et al. (2019). The adeno-associated virus rh10 vector is an effective gene transfer system for chronic spinal cord injury. Sci Rep. 9(1):9844. doi: 10.1038/s41598-019-46069-z.
  18. van Hameren, G. et al. (2019). In vivo real-time dynamics of ATP and ROS production in axonal mitochondria show decoupling in mouse models of peripheral neuropathies. Acta Neuropathol Commun. 7(1):13. doi: 10.1186/s40478-019-0740-4.
  19. Andrzejewski, S. et al. (2019). Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus. Gene Ther. doi: 10.1038/s41434-019-0076-5.
  20. Jang, M. et al. (2019). Gintonin, a ginseng-derived ingredient, as a novel therapeutic strategy for Huntington's disease: Activation of the Nrf2 pathway through lysophosphatidic acid receptors. Brain Behav Immun. pii: S0889-1591(18)30392-1. doi: 10.1016/j.bbi.2019.03.001.
  21. Nakamura, M. et al. (2019). Glycogen Synthase Kinase-3α Promotes Fatty Acid Uptake and Lipotoxic Cardiomyopathy. Cell Metab. pii: S1550-4131(19)30005-1. doi: 10.1016/j.cmet.2019.01.005.
  22. Cho, M. et al. (2019). Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics. Gene Ther. doi: 10.1038/s41434-019-0057-8.
  23. Sato, K. et al. (2018). Ecel1 Knockdown With an AAV2-Mediated CRISPR/Cas9 System Promotes Optic Nerve Damage-Induced RGC Death in the Mouse Retina. Invest Ophthalmol Vis Sci. 59(10):3943-3951. doi: 10.1167/iovs.18-23784.
  24. Kraus, K. et al. (2018). A Fragment of Adhesion Molecule L1 Binds to Nuclear Receptors to Regulate Synaptic Plasticity and Motor Coordination. Mol Neurobiol. 55(9):7164-7178. doi: 10.1007/s12035-018-0901-7.
  25. Koh, W. et al. (2017). AAV-Mediated Astrocyte-Specific Gene Expression under Human ALDH1L1 Promoter in Mouse Thalamus. Exp Neurobiol. 26(6):350-361. doi: 10.5607/en.2017.26.6.350.
  26. Hashimoto, H. et al. (2016). Study on AAV-mediated gene therapy for diabetes in humanized liver mouse to predict efficacy in humans. Biochem Biophys Res Commun. doi:10.1016/j.bbrc.2016.08.104.
  27. Zhao, T. et al. (2016). Compartment-dependent degradation of mutant huntingtin accounts for its preferential accumulation in neuronal processes. J Neurosci. 36:8317-8328.
  28. Nistal-Villan, E. et al. (2016). A versatile vector for in vivo monitoring of type I interferon induction and signaling. PLoS One. 11:e0152031.
  29. Gonzalez, S. et al. (2016). Blocking mitochondrial calcium release in Schwann cells prevents demyelinating neuropathies. J Clin Invest. doi:10.1172/JCI84505.
  30. Tang, F. L. et al. (2015). VPS35 deficiency or mutation causes dopaminergic neuronal loss by impairing mitochondrial fusion and function. Cell Rep. 12:1631-1643.