Tumor Endothelium Adhesion Assay

96-Well Endothelium & Epithelium Adhesion Assays
  • Quantify interactions between tumor cells and the endothelium
  • Fully quantitative with no manual cell counting
  • Highly sensitive results on a fluorescence plate reader
Email To BuyerPrint this PageCopy Link

Please contact your distributor for pricing.

CytoSelect™ Tumor-endothelium Adhesion Assay
Catalog Number
100 assays
Manual/Data Sheet Download
SDS Download
Product Details

Leukocyte or tumor cell interactions with vascular endothelium consist of a cascade of processes including the firm attachment of cells to endothelial cell adhesion molecules.

The CytoSelect™ Tumor Endothelium Adhesion Assay provides a robust system for the quantitative determination of interactions between tumor cells and endothelium. Adherent cells can be easily quantified on a fluorescence plate reader.

Recent Product Citations
  1. Shimomura, H. et al. (2019). Non-SMC Condensin I Complex Subunit H (NCAPH) Is Associated with Lymphangiogenesis and Drug Resistance in Oral Squamous Cell Carcinoma. J Clin Med. 9(1). pii: E72. doi: 10.3390/jcm9010072.
  2. Gao, R. et al. (2019).  Quasi-ultrafine particles promote cell metastasis via HMGB1-mediated cancer cell adhesion. Environ Pollut. doi: 10.1016/j.envpol.2019.113390.
  3. Gao, R. et al. (2019). Dysfunction of the Hippo-Yap Pathway Drives Lung Cancer Metastasis Induced by 1-Nitropyrene through Adhesion Molecular Activation. Environ Sci Technol Lett. doi: 10.1021/acs.estlett.9b00216.
  4. Jassam, S.A. et al. (2019). Fucosyltransferase 4 and 7 mediates adhesion of non-small cell lung cancer cells to brain-derived endothelial cells and results in modification of the blood-brain-barrier: in vitro investigation of CD15 and CD15s in lung-to-brain metastasis. J Neurooncol. doi: 10.1007/s11060-019-03188-x.
  5. Gao, R. et al (2019). PM2.5-associated nitro-PAH exposure promotes tumor cell metastasis through Hippo-YAP mediated transcriptional regulation. Science of The Total Environment. doi: 10.1016/j.scitotenv.2019.04.420.
  6. Li, D. et al. (2018). Targeting the NRF-2/RHOA/ROCK signaling pathway with a novel aziridonin, YD0514, to suppress breast cancer progression and lung metastasis. Cancer Lett. 424:97-108. doi: 10.1016/j.canlet.2018.03.029.
  7. Sasahira, T. et al. (2018). NIPA-like domain containing 1 is a novel tumor-promoting factor in oral squamous cell carcinoma. J Cancer Res Clin Oncol. 144(5):875-882. doi: 10.1007/s00432-018-2612-x.
  8. Nguyen CH, et al. (2017). Fenofibrate inhibits tumour intravasation by several independent mechanisms in a 3-dimensional co-culture model. Int J Oncol. 50(5):1879-1888. doi: 10.3892/ijo.2017.3956.
  9. Chugh, S. et al. (2016). Loss of N-acetylgalactosaminyltransferase 3 in poorly differentiated pancreatic cancer: augmented aggressiveness and aberrant ErbB family glycosylation. Br J  Cancer. doi:10.1038/bjc.2016.116.
  10. Jassam, S. A. et al. (2015). TNF-α enhancement of CD62E mediates adhesion of non–small cell lung cancer cells to brain endothelium via CD15 in lung-brain metastasis. Neuro Oncol. doi:10.1093/neuonc/nov248.
  11. Finetti, F. et al. (2015). mPGES-1 in prostate cancer controls stemness and amplifies EGFR-driven oncogenicityEndocr Relat Cancer. doi:10.1530/ERC-15-0277.
  12. Yang, M. et al. (2014). IgG expression in trophoblasts derived from placenta and gestational trophoblastic disease and its role in regulating invasion. Immunol Res. 60:91-104.
  13. Sasahira, T. et al. (2014). Transport and Golgi organisation protein 1 is a novel tumour progressive factor in oral squamous cell carcinoma. Eur J Cancer. 50:2142-2151.
  14. Ziemann, A. et al. (2013). CRN2 Enhances the Invasiveness of Glioblastoma Cells. Neuro Oncology. 10.1093/neuonc/nos388 (#CBA-215).
  15. Hernandez, L. et al. (2010). Activation of NF-kB Signaling by Inhibitor of NF-kB Kinase ß Increases Aggeressiveness of Ovarian Cancer. Cancer Res. 70:4005-4014 (#CBA-215).
  16. Gu, L. et al. (2010). Stat5 Promotes Metastatic Behavior of Human Prostate Cancer Cells in Vitro and inV ivo. Endocr. Relat. Cancer. 17:481-493 (#CBA-215).