LDL cholesterol is even more dangerous when it becomes oxidized. Oxidized LDL (OxLDL) is more reactive with surrounding tissues and can collect within the inner-lining of arteries. Macrophages, cholesterol, and other lipids can accumulate at the site (atherosclerosis), ultimately forming a plaque that can lead to heart attack, stroke or death. Oxidation of LDL affects both the lipid and protein components of LDL.
The OxiSelect™ Human Oxidized LDL ELISA Kit is an enzyme immunoassay developed for the detection and quantitation of human oxidized LDL in plasma, serum or other biological fluid samples. The kit contains a copper oxidized LDL standard against which unknown samples may be compared. Each oxidized LDL assay is configured to selectively measure either CML-LDL, HNE-LDL, or MDA-LDL.