Selection Guide for Recombinant Viruses for Gene Delivery

Use the following table to help choose the right viral vector for your gene expression studies:

  Adenovirus AAV Lentivirus Retrovirus
Gene Expression Transient Transient or Stable Transient or Stable Stable
Infect Dividing Cells Yes Yes Yes Yes
Infect Non-Dividing Cells Yes Yes Yes No
Integration into Target Cell Genome No No* Yes Yes
Immune Response in Target Cells High Very Low Low Moderate
Relative Viral Titer XXXX XXX XXX XX
Relative Transduction Efficiency XXXX XXX XXX XX

*Native AAV will integrate, but recombinant AAV rarely does.

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