Cellular proteins are subject to oxidative stress in the presence of a variety of reactive oxygen species (ROS). Depending on the ROS present, the resulting damage to the protein may take the form of nitration or oxidation of various amino acid residues. Formation of advanced oxidation protein products (AOPP) is also a marker of oxidative stress.

Our Protein Carbonyl Assays and Protein Nitration Assays provide a quick, sensitive method for detection of carbonyl residues and 3-nitrotyrosine residues, respectively. Both are available in a convenient Western blot format as well as a higher-throughput ELISA. The AOPP assay provides very fast results in a standard microplate reader.