8-OHG RNA Damage ELISA

8-OHG RNA Damage ELISA
  • ELISA detects 300 pg/mL to 40 ng/mL of 8-OHG
  • Suitable for use with RNA from urine, serum, cerebrospinal fluid, cells or tissues
  • 8-OHG standard included for absolute quantitation

 

Frequently Asked Questions about this product

General FAQs about Oxidative Stress

Video: Color Development in an ELISA

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OxiSelect™ Oxidative RNA Damage ELISA Kit (8-OHG Quantitation)
Catalog Number
STA-325-5
Size
5 x 96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$3,595.00
OxiSelect™ Oxidative RNA Damage ELISA Kit (8-OHG Quantitation)
Catalog Number
STA-325
Size
96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$835.00
Product Details

Recently oxidative RNA damage has been described in conjunction with a wide variety of neurological diseases including Alzheimer’s disease, Parkinson’s disease, Dementia with Lewy Bodies, prion disease, and subacute sclerosing panencephalitis.

We have developed an easy-to-use ELISA for the detection of the most common marker of RNA damage: 8-hydroxyguanosine (8-OHG).

8-OHG ELISA Standard Curve

Recent Product Citations
  1. Li, H. et al. (2021). Striatal oxidative damages and neuroinflammation correlate with progression and survival of Lewy body and Alzheimer diseases. Neural Regen Res. 17(4):867-874. doi: 10.4103/1673-5374.322463.
  2. Pappas-Gogos, G. et al. (2021). Urine 8-Hydroxyguanine (8-OHG) in Patients Undergoing Surgery for Colorectal Cancer. J Invest Surg. doi: 10.1080/08941939.2021.1904466.
  3. Li, H. et al. (2019). The Interactions of Dopamine and Oxidative Damage in the Striatum of Neurodegenerative Diseases Patients. J Neurochem. doi: 10.1111/jnc.14898.
  4. Gmitterová, K. et al. (2018). DNA versus RNA oxidation in Parkinson's disease: Which is more important?. Neurosci Lett. 662:22-28. doi: 10.1016/j.neulet.2017.09.048.
  5. Siegfried,C.J. et al (2017).Effects of Vitrectomy and Lensectomy on Older Rhesus Macaques: Oxygen Distribution, Antioxidant Status, and Aqueous Humor Dynamics. Invest Ophthalmol Vis Sci. 58(10):4003-4014. doi: 10.1167/iovs.17-21890.
  6. Sliwinska, A. et al. (2016). The levels of 7, 8-dihydrodeoxyguanosine (8-oxoG) and 8-oxoguanine DNA glycosylase 1 (OGG1)–A potential diagnostic biomarkers of Alzheimer's disease. J Neurol Sci. 368:155-159.
  7. Belenky, P. et al. (2015).  Bactericidal antibiotics induce toxic metabolic perturbations that lead to cellular damage. Cell Rep. 13:968-980.
  8. Tsai, C. H. et al. (2015). Transcriptional Analysis of Deinococcus radiodurans Reveals Novel Small RNAs That Are Differentially Expressed under Ionizing Radiation. Appl Environ Microbiol. 81:1754-1764.
  9. Giannakopoulos, B. et al. (2014). Deletion of the antiphospholipid syndrome autoantigen β2‐glycoprotein I potentiates the lupus autoimmune phenotype in a Toll‐like receptor 7–mediated murine model. Arthritis Rheumatol. 66:2270-2280.
  10. Bazin, J. et al. (2011). Targeted mRNA Oxidation Regulates Sunflower Seed Dormancy Alleviation during Dry after-Ripening. Plant Cell 23:2196-2208.