Platinum-GP (Plat-GP) Retroviral Packaging Cell Line

  • Higher retroviral yields: average titer 106 to 107 infectious units/mL with transient transfection
  • Longer stability: up to 4 months in the presence of drug selection
  • Produce VSVG-pseudotyped pantropic retrovirus, which can easily infect cells of nearly any species

 

NOTE: Platinum Retroviral Packaging Cells are available for sale to academic, government and non-profit research laboratories. All other purchasers require a commercial license for all fields including research use. Please contact our Business Development department for license information.

 

Frequently Asked Questions about this product

General FAQs about Viral Gene Delivery

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Platinum-GP Retroviral Packaging Cell Line, Pantropic
Catalog Number
RV-103
Size
1 vial
Detection
N/A
Manual/Data Sheet Download
SDS Download
Price
$750.00
Product Details

Conventional cells used for retrovirus packaging, such as those based on NIH3T3 cells, have limited stability and produce relatively low yields of retrovirus, mainly due to the poor expression of retroviral structure proteins (gag, pol and env) in the cells.

The Platinum Retroviral Packaging Cell Lines are based on the 293T cell line. They exhibit longer stability and produce higher yields of retroviral structure proteins. Plat-GP cells contain the gag and pol genes required for retroviral packaging; an expression vector is co-transfected with a VSVG envelope vector.

Recent Product Citations
  1. Cavnar, P.J. et al. (2011). Hax1 Regulates Neutrophil Adhesion and Motility through RhoA. J. Cell Biol. 193:465-473.