Guanine Assay Kit

Guanine Assay Kit
  • Detects guanine levels as low as 3.1 µM
  • Compatible with cell or tissue lysates, serum, plasma, or urine
  • Guanine standard included
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Guanine Assay Kit (Colorimetric)
Catalog Number
MET-5147
Size
100 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$415.00
Guanine Assay Kit (Fluorometric)
Catalog Number
MET-5148
Size
100 assays
Detection
Fluorometric
Manual/Data Sheet Download
SDS Download
Price
$415.00
Product Details

Guanine is one of the four common nucleobases of the nucleic acids deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).  In double stranded DNA, guanine forms base pairs with cytosine on the opposite strand, while RNA strands can also fold into secondary structure such as hairpin loops stabilized by the same guanine/cytosine base pairing.  Binding occurs through three hydrogen bonds.  Guanine is synthesized in cells by guanosine phosphorylase from guanosine and phosphate.

Guanine plays a number of biological roles including camouflage, display, and vision.  In addition some amphibians, spiders, and scorpions convert ammonia to guanine, the latter of which can be excreted with minimal loss of water.  Interestingly, it has been reported based on NASA studies of meteorites containing guanine and other nucleobases that guanine can be formed extraterrestrially.