8-OHG RNA Damage ELISA

8-OHG RNA Damage ELISA
  • ELISA detects 300 pg/mL to 40 ng/mL of 8-OHG
  • Suitable for use with RNA from urine, serum, cerebrospinal fluid, cells or tissues
  • 8-OHG standard included for absolute quantitation

 

Frequently Asked Questions about this product

General FAQs about Oxidative Stress

Video: Color Development in an ELISA

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OxiSelect™ Oxidative RNA Damage ELISA Kit (8-OHG Quantitation)
Catalog Number
STA-325-5
Size
5 x 96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$3,465.00
OxiSelect™ Oxidative RNA Damage ELISA Kit (8-OHG Quantitation)
Catalog Number
STA-325
Size
96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$805.00
Product Details

Recently oxidative RNA damage has been described in conjunction with a wide variety of neurological diseases including Alzheimer’s disease, Parkinson’s disease, Dementia with Lewy Bodies, prion disease, and subacute sclerosing panencephalitis.

We have developed an easy-to-use ELISA for the detection of the most common marker of RNA damage: 8-hydroxyguanosine (8-OHG).

8-OHG ELISA Standard Curve

Recent Product Citations
  1. Li, H. et al. (2019). The Interactions of Dopamine and Oxidative Damage in the Striatum of Neurodegenerative Diseases Patients. J Neurochem. doi: 10.1111/jnc.14898.
  2. Gmitterová, K. et al. (2018). DNA versus RNA oxidation in Parkinson's disease: Which is more important?. Neurosci Lett. 662:22-28. doi: 10.1016/j.neulet.2017.09.048.
  3. Siegfried,C.J. et al (2017).Effects of Vitrectomy and Lensectomy on Older Rhesus Macaques: Oxygen Distribution, Antioxidant Status, and Aqueous Humor Dynamics. Invest Ophthalmol Vis Sci. 58(10):4003-4014. doi: 10.1167/iovs.17-21890.
  4. Sliwinska, A. et al. (2016). The levels of 7, 8-dihydrodeoxyguanosine (8-oxoG) and 8-oxoguanine DNA glycosylase 1 (OGG1)–A potential diagnostic biomarkers of Alzheimer's disease. J Neurol Sci. 368:155-159.
  5. Belenky, P. et al. (2015).  Bactericidal antibiotics induce toxic metabolic perturbations that lead to cellular damage. Cell Rep. 13:968-980.
  6. Tsai, C. H. et al. (2015). Transcriptional Analysis of Deinococcus radiodurans Reveals Novel Small RNAs That Are Differentially Expressed under Ionizing Radiation. Appl Environ Microbiol. 81:1754-1764.
  7. Giannakopoulos, B. et al. (2014). Deletion of the antiphospholipid syndrome autoantigen β2‐glycoprotein I potentiates the lupus autoimmune phenotype in a Toll‐like receptor 7–mediated murine model. Arthritis Rheumatol. 66:2270-2280.
  8. Bazin, J. et al. (2011). Targeted mRNA Oxidation Regulates Sunflower Seed Dormancy Alleviation during Dry after-Ripening. Plant Cell 23:2196-2208.