BPDE DNA Adduct ELISA

BPDE DNA Adduct ELISA
  • For detection and quantitation of benzo(a)pyrene diol epoxide (BPDE) DNA adducts
  • BPDE-DNA standard included
  • Suitable for use with DNA samples such as cell or tissue genomic DNA

 

Video: Color Development in an ELISA

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OxiSelect™ BPDE DNA Adduct ELISA Kit
Catalog Number
STA-357
Size
96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$635.00
Product Details

BPDE-DNA standards or unknown DNA samples are adsorbed onto a 96-well DNA high-binding plate. The BPDE-DNA adducts present in the sample or standard are probed with an Anti-BPDE-I Antibody, followed by an HRP Conjugated Secondary Antibody. The BPDE-DNA adduct content in an unknown sample is determined by comparing with a standard curve that is prepared from predetermined BPDE-DNA standards.

BPDE-DNA Standard Curve.

Recent Product Citations
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  2. Kim, J. et al. (2021). Protective Effects of Maclurin against Benzo[a]pyrene via Aryl Hydrocarbon Receptor and Nuclear Factor Erythroid 2-Related Factor 2 Targeting. Antioxidants. 10(8):1189. doi: 10.3390/antiox10081189.
  3. Marchetti, S. et al. (2021). Combustion-derived particles from biomass sources differently promote epithelial-to-mesenchymal transition on A549 cells. Arch Toxicol.  doi: 10.1007/s00204-021-02983-8.
  4. Lin, D. et al. (2020). Influence of postnatal polycyclic aromatic hydrocarbon exposure on the neurodevelopment of toddlers at the age of 12 months. Neurotoxicology. doi: 10.1016/j.neuro.2020.10.013.
  5. Jee, S.C. et al. (2020). Modulatory Effects of Silymarin on Benzo[a]pyrene-Induced Hepatotoxicity. Int J Mol Sci. 21(7). pii: E2369. doi: 10.3390/ijms21072369.
  6. Wang, Z. et al. (2020). Arsenic and benzo[a]pyrene co-exposure acts synergistically in inducing cancer stem cell-like property and tumorigenesis by epigenetically down-regulating SOCS3 expression. Environ Int. 137:105560. doi: 10.1016/j.envint.2020.105560.
  7. Zhang, Y. et al. (2019). Effect of Benzo[a]pyrene-DNA Adduct in Cord Blood on the Neurodevelopment of 12-Month-Old Infants in Qingdao City. Neuropsychiatr Dis Treat. 15:3351-3357. doi: 10.2147/NDT.S219244.
  8. Coric, V. M. et al. (2016). Combined GSTM1-Null, GSTT1-Active, GSTA1 Low-Activity and GSTP1-Variant Genotype is associated with increased risk of clear cell renal cell carcinoma. PLoS One. doi:10.1371/journal.pone.0160570.
  9. Barhoumi, R. et al. (2014). Effects of fatty acids on benzo [a] pyrene uptake and metabolism in human lung adenocarcinoma A549 cells. PLoS One. 9:e90908.
  10. Borska, L. et al. (2014). Oxidative damage to nucleic acids and benzo (a) pyrene-7, 8-diol-9, 10-epoxide-DNA adducts and chromosomal aberration in children with psoriasis repeatedly exposed to crude coal tar ointment and UV radiation. Oxid Med Cell Longev. doi:10.1155/2014/302528.