Human Oxidized LDL ELISA Kit (MDA-LDL)

Human Oxidized LDL ELISA Kit (MDA-LDL)
  • Suitable for use with human plasma or serum samples
  • Copper oxidized LDL (oxLDL) Standard included
  • Detection sensitivity limit of <50 ng/mL for MDA-LDL

 

Frequently Asked Questions about this product

Video: Color Development in an ELISA

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OxiSelect™ Human Oxidized LDL ELISA Kit (MDA-LDL Quantitation)
Catalog Number
STA-369
Size
96 assays
Detection
Colorimetric
Price
$740.00
Product Details

LDL, so-called "bad cholesterol", is even more dangerous when it becomes oxidized. Oxidized LDL (OxLDL) is more reactive with surrounding tissues and can collect within the inner-lining of arteries. Macrophages, cholesterol, and other lipids can accumulate at the site (atherosclerosis), ultimately forming a plaque that can lead to heart attack, stroke or death. Oxidation of LDL affects both the lipid and protein components of LDL

The OxiSelect™ Human Oxidized LDL ELISA Kits are enzyme immunoassays developed for the detection and quantitation of human oxLDL in plasma, serum or other biological fluid samples. The kits contain a copper oxidized LDL standard against which unknown samples may be compared. This oxidized LDL assay kit is configured to selectively measure oxLDL in MDA-LDL.

Note: MDA is the most prevalent modification found in oxidized LDL, but it is not stable in samples stored for more than one month. Our MDA-LDL assay is best for use with fresh samples. For samples stored for longer periods, better results may be obtained with measurement of CML or HNE modifications, both of which are more stable than MDA.

Assay Principle for the OxiSelect™ Oxidized LDL ELISA Kits.

Standard Curve Generated with the OxiSelect™ Oxidized LDL ELISA Kit (MDA-LDL Quantitation).

Recent Product Citations
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  3. Oguazu, C.E. et al. (2021). Bisphenol a Exposure Causes Increased Oxidation of Low Density Lipoprotein (LDL) and Its Abduct in Rats. Asian J. Res. Biochem. 9(2):1-10. doi: 10.9734/AJRB/2021/v9i230195.
  4. Galvis-Pérez, Y. et al. (2020). Comparative Evaluation of the Effects of Consumption of Colombian Agraz (Vaccinium meridionale Swartz) on Insulin Resistance, Antioxidant Capacity, and Markers of Oxidation and Inflammation, Between Men and Women with Metabolic Syndrome. Biores Open Access. 9(1):247-254. doi: 10.1089/biores.2020.0053.
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  7. Pokimica, B. et al. (2019). Chokeberry Juice Containing Polyphenols Does Not Affect Cholesterol or Blood Pressure but Modifies the Composition of Plasma Phospholipids Fatty Acids in Individuals at Cardiovascular Risk. Nutrients. 11(4). pii: E850. doi: 10.3390/nu11040850.
  8. Liu, Q. et al. (2018). Entire Peroxidation Reaction System of Myeloperoxidase Correlates with Progressive Low-Density Lipoprotein Modifications via Reactive Aldehydes in Atherosclerotic Patients with Hypertension. Cell Physiol Biochem. 50(4):1245-1254. doi: 10.1159/000494579.
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  10. Wang, F. et al. (2015). Shift of the interconnection from the reaction system of paraoxonase 1 to the peroxidation reaction system of myeloperoxidase with HDL-C levels: a marker of atherosclerosis in patients with normal cholesterol levels. Clin Chim Acta. 438:370-375.
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