AAV-6 Rep-Cap Plasmid

AAV-6 Rep-Cap Plasmid
  • Use one of our AAV Rep-Cap plasmids along with the AAV Helper Free System to produce recombinant human adeno associated virus (rAAV) virions without the need for a helper virus
  • Ideal if you already have the AAV Helper Free System but would like to try a different AAV serotype

 

Frequently Asked Questions about AAV Expression and Packaging

General FAQs about using AAV

General FAQs about Viral Gene Delivery

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pAAV-RC6 Vector
Catalog Number
VPK-426
Size
10 µg
Detection
N/A
Manual/Data Sheet Download
SDS Download
Map Download
Sequence Download
Price
$555.00
Product Details

Recombinant adeno-associated viruses are important tools for gene delivery and expression.  AAV has not been reported to cause any diseases.  Together with its replication defective nature, AAV has good safety profile to be used in gene transfer in vivo, and as potential gene therapy vehicles. 

Our AAV Rep-Cap plasmids work with our AAV Helper Free Systems to produce recombinant AAV more safely and easily, without the need for a helper virus. Choose one of these plasmids if you already have the AAV Helper Free System and would like to try a different AAV serotype.

Recent Product Citations
  1. Tian, F. et al. (2026). STUB1-induced polyubiquitination of SIK3 in alveolar type 2 epithelial cells alleviates severity and outcomes of acute lung injury. Cell Death Dis. doi: 10.1038/s41419-026-08822-x.
  2. Bai, R.Y. et al. (2025). Development of an adeno-associated virus vector for gene replacement therapy of NF1-related tumors. Nat Commun. 16(1):8594. doi: 10.1038/s41467-025-63619-4.
  3. Coughlin, G.M. et al. (2025). Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo. Nat Biotechnol. doi: 10.1038/s41587-025-02565-4.
  4. Xie, Y. & Butler, M. (2023). N-glycomic profiling of capsid proteins from adeno-associated virus serotypes. Glycobiology. doi: 10.1093/glycob/cwad074.
  5. Katada, Y. et al. (2023). Highly sensitive visual restoration and protection via ectopic expression of chimeric rhodopsin in mice. iScience. 26(10):107716. doi: 10.1016/j.isci.2023.107716.
  6. Ling, X. et al. (2022). Efficient generation of locus-specific human CAR-T cells with CRISPR/cCas12a. STAR Protoc. 3(2):101321. doi: 10.1016/j.xpro.2022.101321.
  7. Chen, S.H. et al. (2020). A Simple, Two-Step, Small-Scale Purification of Recombinant Adeno-Associated Viruses. J Virol Methods. doi: 10.1016/j.jviromet.2020.113863.
  8. Romeo, C. et al. (2020). AAV diffuses across zona pellucida for effortless gene delivery to fertilized eggs. Biochem Biophys Res Commun. pii: S0006-291X(20)30505-2. doi: 10.1016/j.bbrc.2020.03.026.
  9. Hoshino, Y. et al. (2019). The adeno-associated virus rh10 vector is an effective gene transfer system for chronic spinal cord injury. Sci Rep. 9(1):9844. doi: 10.1038/s41598-019-46069-z.