AAV CMV Expression Vector

AAV CMV Expression Vector
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pAAV-MCS Expression Vector
Catalog Number
VPK-410
Size
10 µg
Detection
N/A
Manual/Data Sheet Download
SDS Download
Map Download
Sequence Download
Price
$515.00
Product Details

Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

Recent Product Citations
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  2. Deng, X. et al. (2020). Establishment of a Recombinant AAV2/HBoV1 Vector Production System in Insect Cells. Genes (Basel). 11(4). pii: E439. doi: 10.3390/genes11040439.
  3. Jang, M. et al. (2018). Adeno-Associated Viral Vector Serotype DJ-Mediated Overexpression of N171-82Q-Mutant Huntingtin in the Striatum of Juvenile Mice Is a New Model for Huntington's Disease. Front Cell Neurosci. 12:157. doi: 10.3389/fncel.2018.00157.
  4. Hoshino, Y. et al. (2019). The adeno-associated virus rh10 vector is an effective gene transfer system for chronic spinal cord injury. Sci Rep. 9(1):9844. doi: 10.1038/s41598-019-46069-z.
  5. van Hameren, G. et al. (2019). In vivo real-time dynamics of ATP and ROS production in axonal mitochondria show decoupling in mouse models of peripheral neuropathies. Acta Neuropathol Commun. 7(1):13. doi: 10.1186/s40478-019-0740-4.
  6. Andrzejewski, S. et al. (2019). Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus. Gene Ther. doi: 10.1038/s41434-019-0076-5.
  7. Jang, M. et al. (2019). Gintonin, a ginseng-derived ingredient, as a novel therapeutic strategy for Huntington's disease: Activation of the Nrf2 pathway through lysophosphatidic acid receptors. Brain Behav Immun. pii: S0889-1591(18)30392-1. doi: 10.1016/j.bbi.2019.03.001.
  8. Nakamura, M. et al. (2019). Glycogen Synthase Kinase-3α Promotes Fatty Acid Uptake and Lipotoxic Cardiomyopathy. Cell Metab. pii: S1550-4131(19)30005-1. doi: 10.1016/j.cmet.2019.01.005.
  9. Cho, M. et al. (2019). Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics. Gene Ther. doi: 10.1038/s41434-019-0057-8.
  10. Jang, M. et al. (2018). Adeno-Associated Viral Vector Serotype DJ-Mediated Overexpression of N171-82Q-Mutant Huntingtin in the Striatum of Juvenile Mice Is a New Model for Huntington's Disease. Front Cell Neurosci. 12:157. doi: 10.3389/fncel.2018.00157.
  11. Van Hameren, G. et al. (2018). CMT disease 2A and demyelination decouple ATP and ROS production by axonal mitochondria. bioRxiv. 462523. doi: 10.1101/462523.
  12. Sato, K. et al. (2018). Ecel1 Knockdown With an AAV2-Mediated CRISPR/Cas9 System Promotes Optic Nerve Damage-Induced RGC Death in the Mouse Retina. Invest Ophthalmol Vis Sci. 59(10):3943-3951. doi: 10.1167/iovs.18-23784.
  13. Kraus, K. et al. (2018). A Fragment of Adhesion Molecule L1 Binds to Nuclear Receptors to Regulate Synaptic Plasticity and Motor Coordination. Mol Neurobiol. 55(9):7164-7178. doi: 10.1007/s12035-018-0901-7.
  14. Koh, W. et al. (2017). AAV-Mediated Astrocyte-Specific Gene Expression under Human ALDH1L1 Promoter in Mouse Thalamus. Exp Neurobiol. 26(6):350-361. doi: 10.5607/en.2017.26.6.350.
  15. Hashimoto, H. et al. (2016). Study on AAV-mediated gene therapy for diabetes in humanized liver mouse to predict efficacy in humans. Biochem Biophys Res Commun. doi:10.1016/j.bbrc.2016.08.104.
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  17. Nistal-Villan, E. et al. (2016). A versatile vector for in vivo monitoring of type I interferon induction and signaling. PLoS One. 11:e0152031.
  18. Gonzalez, S. et al. (2016). Blocking mitochondrial calcium release in Schwann cells prevents demyelinating neuropathies. J Clin Invest. doi:10.1172/JCI84505.
  19. Tang, F. L. et al. (2015). VPS35 deficiency or mutation causes dopaminergic neuronal loss by impairing mitochondrial fusion and function. Cell Rep. 12:1631-1643.
  20. Orabi, A. I. et al. (2015). Dynamic imaging of pancreatic NF-κB activation in live mice using AAV infusion and bioluminescence. J Biol Chem. doi:10.1074/jbc.M115.647933.
  21. Fyk-Kolodziej, B. et al. (2014). Marking Cells With Infrared Fluorescent Proteins to Preserve Photoresponsiveness in the Retina. Biotechniques. 57:245-253.
  22. Lutz, D. et al. (2014).  Myelin Basic Protein Cleaves Cell Adhesion Molecule L1 and Promotes Neuritogenesis and Cell Survival. J Biol Chem. 289:13503-13518.
  23. Yan, S. et al. (2014).  TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain. Hum Mol Genet. 23:2678-2693.