Advanced Oxidation Protein Products (AOPP) Assay

  • Measure AOPP formation in cell lysates, tissue homogenates, or plasma
  • Obtain results in less than 30 minutes
  • Quantify results on a standard microplate reader


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General FAQs about Oxidative Stress

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AOPP-Human Serum Albumin (AOPP-HSA)
Catalog Number
50 µL
Manual/Data Sheet Download
SDS Download
OxiSelect™ AOPP Assay Kit
Catalog Number
200 assays
Manual/Data Sheet Download
SDS Download
Product Details

Advanced Oxidation Protein Products (AOPP) are uremic toxins created during oxidative stress through the reaction of plasma proteins with chlorinated oxidants such as chloramines or hypochlorous acid. AOPP levels are elevated in patients with renal complications, diabetes mellitus, and atherosclerosis, as well as HIV-positive patients.

Our OxiSelect™ AOPP Assay Kit provides a convenient method to assess oxidative stress. The kit includes a Chloramine standard and an AOPP Human Serum Albumin conjugate for use as a positive control.

Chloramine Standard Curve Generated with the OxiSelect™ AOPP Assay Kit.

AOPP-HSA Positive Control. Positive control and untreated HSA were both prepared at a concentration of 100 µM and tested according to the assay protocol.

Recent Product Citations
  1. Wan, X. et al. (2016). SIRT1-PGC1a-NFkB pathway of oxidative and inflammatory stress during Trypanosoma cruzi infection: benefits of SIRT1-targeted therapy in improving heart function in Chagas disease. PLoS Pathog. doi:10.1371/journal.ppat.1005954.
  2. Gradinaru, D. et al. (2016). Adiponectin: possible link between metabolic stress and oxidative stress in the elderly. Aging Clin Exp Res. doi:10.1007/s40520-016-0629-z.
  3. Crone, L. B. et al. (2016). Impact of meal ingestion rate and caffeine coingestion on postprandial lipemia and oxidative stress following high-fat meal consumption. J Caffeine Res. doi:10.1089/jcr.2016.0004.
  4. Huemer, M. et al. (2016). Clinical phenotype, biochemical profile, and treatment in 19 patients with arginase 1 deficiency. J Inherit Metab Dis. doi:10.1007/s10545-016-9928-y.
  5. Martins, L. S. et al. (2015). Advanced Glycation Endproducts (AGE) evolution after pancreas-kidney transplantation: plasmatic and cutaneous assessments. Oxid Med Cell Longev. 2189582.
  6. Šarić, B. et al. (2015). Oxidative stress impact on growth hormone secretion in the eye. Croat Med J. 56:326-333.
  7. Bloomer, R. J. et al. (2015). Comparison of a restricted and unrestricted vegan diet plan with a restricted omnivorous diet plan on health-specific measures. Healthcare.3:544-555. 
  8. Jung, E. et al. (2015). Gemigliptin improves renal function and attenuates podocyte injury in mice with diabetic nephropathy. Eur J Pharmacol. doi: 10.1016/j.ejphar.2015.04.055.
  9. Thurmond, P. et al. (2015). Structural modifications of the prostate in hypoxia, oxidative stress, and chronic ischemia. Korean J Urol. 56:187-196.
  10. Xie, Z. X. et al. (2014). Effect of GABA on oxidative stress in the skeletal muscles and plasma free amino acids in mice fed high-fat diet. J Anim Physiol Anim Nutr (Berl). doi: 10.1111/jpn.12254.
  11. Witthaus, M. W. et al. (2014). Bladder oxidative stress in sleep apnea contributes to detrusor instability and nocturia. J Urol. doi: 10.1016/j.juro.2014.11.055.
  12. Zhang, Q. et al. (2014). Effects of ischemia and oxidative stress on bladder purinoceptors expression. Urology 84:e1-e7.
  13. Xie, F. et al. (2014). Advanced oxidation protein products induce intestine epithelial cell death through a redox-dependent, c-jun N-terminal kinase and poly (ADP-ribose) polymerase-1-mediated pathway. Cell Death Dis. 5:e1006.
  14. Umanskaya, A. et al. (2014).  Genetically Enhancing Mitochondrial Antioxidant Activity Improves Muscle Function in Aging. Proc Natl Acad Sci U S A. 111:15250-15255.
  15. Bloomer, R. et al. (2013). Safety Profile of Caffeine and 1,3-dimethylamylamine Supplementation in Healthy Men. Human and Experimental Toxicology. 10.1177/0960327113475680 (#STA-318).
  16. Park, S.H. et al. (2012). Effects of Neutral pH and Low-Glucose DegradationPproduct-Containing Peritoneal Dialysis Fluid on Systemic Markers of Inflammation and Endothelial Dysfunction: a Randomized Controlled 1-Year Follow-Up Study. Nephrol. Dial. Transp. 27:1191-1199. (#STA-318).
  17. Anderson, D. et al. (2010). Albumin-based Microbubbles Bind Up-regulated Scavenger Receptors following Vascular Injury. J. BiolChem. 285:40645-40653. (#STA-318).