Pantropic Promoterless Lentiviral Expression System

ViraSafe Lentiviral System
  • Significantly reduced homology compared to other 3rd generation expression systems for added safety, without loss of titer
  • Vectors provided individually to allow optimization of vector ratio
  • Complete Expression System contains packaging plasmids and expression vector
  • Cloning capacity of expression vector = 9.4 kb
  • Resulting VSVG-pseudotyped virus can infect virtually all cells regardless of species of origin

 

Frequently Asked Questions about this product

General FAQs about Viral Gene Delivery

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ViraSafe™ Universal Lentiviral Expression System (Promoterless), Pantropic
Catalog Number
VPK-211-PAN
Size
1 kit
Detection
N/A
Manual/Data Sheet Download
SDS Download
Map Download
Sequence Download
Price
$1,035.00
Product Details

Lentivirus based on HIV-1 provides a powerful means for gene expression because it can infect both dividing and non-dividing cells. Other 3rd generation lentiviral packaging systems provide a reduced risk of replication-competent virus, but a small risk remains.

Our ViraSafe™ Lentivirus Expression Complete Systems provide a safer method even compared to other 3rd generation expression systems. Overlap with native HIV genes has been reduced much further, thereby substantially reducing the chance of generating replication-competent virus. The system has been engineered so that lentiviral titers remain at the levels of third generation systems.

The Pantropic Expression Systems assemble VSVG-pseudotyped lentiviruses which can easily infect virtually any cells regardless of their species of origin.

Lentivirus Production using the ViraSafe™ Lentivirus Expression System.

Recent Product Citations

Hagen, J.T. et al. (2025). Acute myeloid leukemia mitochondria hydrolyze ATP to support oxidative metabolism and resist chemotherapy. Sci Adv. 11(15):eadu5511. doi: 10.1126/sciadv.adu5511.