Poly ADP-ribosylation (PAR) is involved in various biological functions, but one of the most studies roles is the generation of PAR chains in response to DNA damage. Such PAR chains recruit repair proteins and chromatin remodelers, enhancing DNA repair processes.
Our Poly (ADP-Ribose) ELISA Kit provides for rapid detection and quantitation of PAR levels in cell or tissue samples. The quantity of PAR in unknown samples is determined by comparing its optical density with that of a known standard curve. Each kit provides sufficient reagents to perform up to 96 assays, including standards and unknown samples.