AAV-LK03 Rep-Cap Plasmid

AAV-LK03 Rep-Cap Plasmid
  • Use this AAV Rep-Cap plasmid along with the AAV Helper Free System to produce recombinant human adeno associated virus (rAAV) virions without the need for a helper virus
  • Ideal if you already have the AAV Helper Free System with a different AAV serotype
  • Increase transduction efficiency of primary human hepatocytes


NOTE: pAAV-LK03 is available for sale to academic, government and non-profit research laboratories. All other purchasers require a commercial license for all fields including research use. Please contact our Business Development department for license information.

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AAV-LK03 Rep-Cap Plasmid
Catalog Number
10 µg
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SDS Download
Map Download
Sequence Download
Product Details

Adeno-associated virus (AAV) serotypes differ broadly in transduction efficacies and tissue tropisms. DNA family shuffling technology was used to create a complex library of hybrid capsids from ten different wild-type viruses. Stringent selection of AAV variants in vivo using FRG mice partially repopulated with primary human hepatocytes results in AAV-LK03. In comparison to AAV-DJ, which efficiently transduces most mouse and human cells in culture, AAV-LK03 preferentially transduces human cells. Importantly, AAV-LK03 transduces primary human hepatocytes 100-fold better than AAV8.