Tumor Transendothelial Migration Assay

Tumor Transendothelial Migration Assay
  • Quantify interactions between endothelium and tumor cells
  • Fully quantify cell transmigration with no manual cell counting
  • Highly sensitive results on a fluorescence plate reader

 

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CytoSelect™ Tumor Transendothelial Migration Assay
Catalog Number
CBA-216
Size
24 assays
Detection
Fluorometric
Manual/Data Sheet Download
SDS Download
Price
$625.00
Product Details

Cancer cell transmigration, particularly extravasation, is an important step in cancer metastasis. It is the final step in a cascade of interactions between cells and the endothelium.

CytoSelect™ Tumor Transendothelial Migration Assay provides a robust system for the quantitative determination of transmigrations and interactions between endothelium and tumor cells. Migratory cells may be quantified on a fluorescence plate reader. Kits use 24-well plates with 8 µm pore size membrane inserts.

Recent Product Citations
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  6. Park, G.B. et al. (2019). Modified TLR-mediated downregulation of miR-125b-5p enhances CD248 (endosialin)-induced metastasis and drug resistance in colorectal cancer cells. Mol Carcinog. doi: 10.1002/mc.23137.
  7. Wang, S.Y. et al. (2019). High Expression of MicroRNA-196a is Associated with Progression of Hepatocellular Carcinoma in Younger Patients. Cancers (Basel). 11(10). pii: E1549. doi: 10.3390/cancers11101549.
  8. Park, G.B. et al. (2019). MicroRNA-503-5p Inhibits the CD97-Mediated JAK2/STAT3 Pathway in Metastatic or Paclitaxel-Resistant Ovarian Cancer Cells. Neoplasia. 21(2):206-215. doi: 10.1016/j.neo.2018.12.005.
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  10. Toeda, Y. et al. (2018). FBLIM1 enhances oral cancer malignancy via modulation of the epidermal growth factor receptor pathway. Mol Carcinog. 57(12):1690-1697. doi: 10.1002/mc.22889.
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  12. Park, G.B. et al. (2017). Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial-mesenchymal transition through the regulation of ADAM10 and ADAM17. Mol Cell Biochem. doi: 10.1007/s11010-017-3148-0.
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  14. Park, G.B. et al. (2017). PI3K Catalytic Isoform Alteration Promotes the LIMK1-related Metastasis Through the PAK1 or ROCK1/2 Activation in Cigarette Smoke-exposed Ovarian Cancer Cells. Anticancer Res. 37(4):1805-1818.
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  18. Park, G. B. et al. (2015). Silencing of galectin-3 represses osteosarcoma cell migration and invasion through inhibition of FAK/Src/Lyn activation and β-catenin expression and increases susceptibility to chemotherapeutic agents.Int J Oncol. 46:185-194.
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