8-OHdG DNA Damage ELISA

8-OHdG DNA Damage ELISA
  • Detect as little as 100 pg/mL of 8-OHdG
  • Suitable for use with urine, serum, cells or tissues
  • 8-OHdG standard included for absolute quantitation

 

Frequently Asked Questions about this product

General FAQs about Oxidative Stress

Video: Color Development in an ELISA

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OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation), Trial Size
Catalog Number
STA-320-T
Size
32 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$415.00
OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation)
Catalog Number
STA-320
Size
96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$835.00
OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation)
Catalog Number
STA-320-5
Size
5 x 96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$3,595.00
Product Details

Among numerous types of oxidative DNA damage, 8-hydroxydeoxyguanosine (8-OHdG) is a ubiquitous marker of oxidative stress. 8-OHdG, one of the byproducts of oxidative DNA damage, is physiologically formed and enhanced by chemical carcinogens.

Our OxiSelect™ Oxidative DNA Damage ELISA Kit (8-hydroxydeoxyguanosine assay) provides a powerful method for rapid, sensitive quantitation of 8-OHdG in DNA samples.

8-OHdG ELISA Standard Curve

8-OHdG Levels in Human Urine.

Recent Product Citations
  1. Ivanova, I. et al. (2022). Investigation of the HelioVital filter foil revealed protective effects against UVA1 irradiation-induced DNA damage and against UVA1-induced expression of matrixmetalloproteinases (MMP) MMP1, MMP2, MMP3 and MMP15. Photochem Photobiol Sci. doi: 10.1007/s43630-022-00177-4.
  2. Tungmunnithum, D. et al. (2022). Flavonoids from Sacred Lotus Stamen Extract Slows Chronological Aging in Yeast Model by Reducing Oxidative Stress and Maintaining Cellular Metabolism. Cells. 11(4):599. doi: 10.3390/cells11040599.
  3. Ding, J. et al. (2022). Exogenous pancreatic kininogenase protects against tacrolimus-induced renal injury by inhibiting PI3K/AKT signaling: The role of bradykinin receptors. Int Immunopharmacol. 105:108547. doi: 10.1016/j.intimp.2022.108547.
  4. Genovese, E. et al. (2022). The Response to Oxidative Damage Correlates with Driver Mutations and Clinical Outcome in Patients with Myelofibrosis. Antioxidants (Basel). 11(1):113. doi: 10.3390/antiox11010113.
  5. Souza, M.A. et al. (2021). Doxycycline hyclate stimulates inducible nitric oxide synthase and arginase imbalance, potentiating inflammatory and oxidative lung damage in schistosomiasis. Biomed J. doi: 10.1016/j.bj.2021.12.007.
  6. Wu, H. et al. (2021). Trabecular meshwork mitochondrial function and oxidative stress: Clues to racial disparities of glaucoma. Ophthalmol Sci. doi: 10.1016/j.xops.2021.100107.
  7. Qi, M. et al. (2021). Inhibition mechanism of high voltage prick electrostatic field (HVPEF) on Staphylococcus aureus through ROS-mediated oxidative stress. LWT. doi: 10.1016/j.lwt.2021.112990.
  8. Zhao, J. et al. (2021). Effect of Plasma-Activated Solution Treatment on Cell Biology of Staphylococcus aureus and Quality of Fresh Lettuces. Foods. 10(12):2976. doi: 10.3390/foods10122976.
  9. Qi, M. et al. (2021). MyD88 deficiency ameliorates weight loss caused by intestinal oxidative injury in an autophagy-dependent mechanism. J Cachexia Sarcopenia Muscle. doi: 10.1002/jcsm.12858.
  10. Hu, W. et al. (2021). Topical Administration of Pterostilbene Accelerates Burn Wound Healing in Diabetes through Activation of HIF1α Signaling Pathway. Burns. doi: 10.1016/j.burns.2021.10.019.
  11. Całyniuk, Z. et al. (2021). Selected metabolic, epigenetic, nitration and redox parameters in turkeys fed diets with different levels of arginine and methionine. Ann. Anim. Sci. doi: 10.2478/aoas-2021-0069.
  12. Chan, T.K. et al. (2021). Polycyclic aromatic hydrocarbons regulate the pigmentation pathway and iinduce DNA damage responses in keratinocytes, a process driven by systemic immunity. J Dermatol Sci. doi: 10.1016/j.jdermsci.2021.09.003.
  13. Kim, H.C. et al. (2021). Glycyrrhizin ameliorating sterile inflammation induced by low-dose radiation exposure. Sci Rep. 11(1):18356. doi: 10.1038/s41598-021-97800-8.
  14. Li, H. et al. (2021). Striatal oxidative damages and neuroinflammation correlate with progression and survival of Lewy body and Alzheimer diseases. Neural Regen Res. 17(4):867-874. doi: 10.4103/1673-5374.322463.
  15. Pérez-Soto, E. et al. (2021). Proinflammatory and Oxidative Stress States Induced by Human Papillomavirus and Chlamydia trachomatis Coinfection Affect Sperm Quality in Asymptomatic Infertile Men. Medicina (Kaunas). 57(9):862. doi: 10.3390/medicina57090862.
  16. Boudjema, J. et al. (2021). Metal enriched quasi-ultrafine particles from stainless steel gas metal arc welding induced genetic and epigenetic alterations in BEAS-2B cells. NanoImpact. doi: 10.1016/j.impact.2021.100346.
  17. Li, J. & Min, Y. (2021). Pre-clinical evidence that salinomycin is active against retinoblastoma via inducing mitochondrial dysfunction, oxidative damage and AMPK activation. J Bioenerg Biomembr. 53(5):513-523. doi: 10.1007/s10863-021-09915-2.
  18. Ognik, K. et al. (2021). The immune status, oxidative and epigenetic changes in tissues of turkeys fed diets with different ratios of arginine and lysine. Sci Rep. 11(1):15975. doi: 10.1038/s41598-021-95529-y.
  19. Wadikar, D.L. et al. (2021). Assessment of occupational exposure to diesel particulate matter through evaluation of 1-nitropyrene and 1-aminopyrene in surface coal miners, India. Environ Monit Assess. 193(6):342. doi: 10.1007/s10661-021-09121-y.
  20. Fatima, S. et al. (2021). Epigallocatechin gallate and coenzyme Q10 attenuate cisplatin-induced hepatotoxicity in rats via targeting mitochondrial stress and apoptosis. J Biochem Mol Toxicol. doi: 10.1002/jbt.22701.
  21. Ahmad, A. et al. (2021). Swertia chirayita suppresses the growth of non-small cell lung cancer A549 cells and concomitantly induces apoptosis via downregulation of JAK1/STAT3 pathway. Saudi J Biol Sci. doi: 10.1016/j.sjbs.2021.06.085.
  22. Xue, Z. et al. (2021). Isorhapontigenin ameliorates cerebral ischemia/reperfusion injury via modulating Kinase Cε/Nrf2/HO-1 signaling pathway. Brain Behav. doi: 10.1002/brb3.2143.
  23. Jiang, J. et al. (2021). Impact of intrauterine fetal resuscitation with oxygen on oxidative stress in the developing rat brain. Sci Rep. 11(1):9798. doi: 10.1038/s41598-021-89299-w.
  24. Jacobson, M.H. et al. (2021). Organophosphate pesticides and progression of chronic kidney disease among children: A prospective cohort study. Environ Int. 155:106597. doi: 10.1016/j.envint.2021.106597.
  25. Oladosu, W.O. et al. (2021). Evaluating the Effects of Life styles and History of Exposure to Radiation on Levels of Significance and Severity of Sperm DNA Damage among Males with Infertility Using 8-Hydroxydeoxyguanosine (8-OHDG) as a Marker. EC Endocrinology and Metabolic Research. 6(4): 15-27.
  26. Shaw, P. et al. (2021). Cold Atmospheric Plasma Increases Temozolomide Sensitivity of Three-Dimensional Glioblastoma Spheroids via Oxidative Stress-Mediated DNA Damage. Cancers. 13(8):1780. doi: 10.3390/cancers13081780.
  27. Sener, T.E. et al. (2020). Effects of resveratrol against scattered radiation-induced testicular damage in rats. Turk Biyokim Derg. doi: 10.1515/tjb-2020-0320.
  28. Corinaldesi, C. et al. (2021). Multiple impacts of microplastics can threaten marine habitat-forming species. Commun Biol. 4(1):431. doi: 10.1038/s42003-021-01961-1.
  29. Wahjuni, S. et al. (2021). Green Mustard Ethanol Extract (Brassica Rapa L.) Leaf Can Cell Damage (8-Hydroxy-2-Dioxiguanosine) In The Wistar Rat Hyperglicemic. IOP Conf. Ser.: Earth Environ. Sci. doi: 10.1088/1755-1315/709/1/012046.
  30. Jankowski, J. et al. (2021). The effect of different dietary ratios of lysine, arginine and methionine on protein nitration and oxidation reactions in turkey tissues and DNA. Animal. doi: 10.1016/j.animal.2021.100183.