8-OHdG DNA Damage ELISA

8-OHdG DNA Damage ELISA
  • Detect as little as 100 pg/mL of 8-OHdG
  • Suitable for use with urine, serum, cells or tissues
  • 8-OHdG standard included for absolute quantitation

 

Frequently Asked Questions about this product

General FAQs about Oxidative Stress

Video: Color Development in an ELISA

Email To BuyerPrint this PageCopy Link
Ordering

Please contact your distributor for pricing.

OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation), Trial Size
Catalog Number
STA-320-T
Size
32 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$415.00
OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation)
Catalog Number
STA-320
Size
96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$835.00
OxiSelect™ Oxidative DNA Damage ELISA Kit (8-OHdG Quantitation)
Catalog Number
STA-320-5
Size
5 x 96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$3,595.00
Product Details

Among numerous types of oxidative DNA damage, 8-hydroxydeoxyguanosine (8-OHdG) is a ubiquitous marker of oxidative stress. 8-OHdG, one of the byproducts of oxidative DNA damage, is physiologically formed and enhanced by chemical carcinogens.

Our OxiSelect™ Oxidative DNA Damage ELISA Kit (8-hydroxydeoxyguanosine assay) provides a powerful method for rapid, sensitive quantitation of 8-OHdG in DNA samples.

8-OHdG ELISA Standard Curve

8-OHdG Levels in Human Urine.

Recent Product Citations
  1. Wang, Y. et al. (2022). Protective effect of hydroxysafflor yellow A on renal ischemia‑reperfusion injury by targeting the Akt‑Nrf2 axis in mice. Exp Ther Med. doi: 10.3892/etm.2022.11677.
  2. Wang, B. et al. (2022). Let-7e-5p, a promising novel biomarker for benzene toxicity, is involved in benzene-induced hematopoietic toxicity through targeting caspase-3 and p21. Ecotoxicol Environ Saf. doi: 10.1016/j.ecoenv.2022.114142.
  3. Ibrahim, M.A. et al. (2022). Bone-Marrow-Derived Mesenchymal Stem Cells, Their Conditioned Media, and Olive Leaf Extract Protect against Cisplatin-Induced Toxicity by Alleviating Oxidative Stress, Inflammation, and Apoptosis in Rats. Toxics. 10(9):526. doi: 10.3390/toxics10090526.
  4. Wang, H. et al. (2022). Biphasic effects of statins on neuron cell functions under oxygen-glucose deprivation and normal culturing conditions via different mechanisms. Pharmacol Res Perspect. 10(5):e01001. doi: 10.1002/prp2.1001.
  5. Ohira, H. et al. (2022). Suppression of colonic oxidative stress caused by chronic ethanol administration and attenuation of ethanol-induced colitis and gut leakiness by oral administration of sesaminol in mice. Food Funct. doi: 10.1039/d1fo04120g.
  6. Fujita, N. et al. (2022). Association of oxidative stress with erectile dysfunction in community-dwelling men and men on dialysis. Aging Male. 25(1):193-201. doi: 10.1080/13685538.2022.2103113.
  7. Del Mar Rivas-Chacón, L. et al. (2022). Preventive Effect of Cocoa Flavonoids via Suppression of Oxidative Stress-Induced Apoptosis in Auditory Senescent Cells. Antioxidants (Basel). 11(8):1450. doi: 10.3390/antiox11081450.
  8. Konieczka, P. et al. (2022). Increased arginine, lysine, and methionine levels can improve the performance, gut integrity and immune status of turkeys but the effect is interactive and depends on challenge conditions. Vet Res. 53(1):59. doi: 10.1186/s13567-022-01080-7.
  9. Muhammed, S. et al. (2022). The Effect of Zingiber, Alpinia Officinarum with Periodontal Therapy on Clinical Outcome and Oxidative Stress. J. Hunan Univ. Nat. Sci. 49(6):32-43. doi: 10.55463/issn.1674-2974.49.6.4.
  10. Dworzański, W. et al. (2022). Oxidative, epigenetic changes and fermentation processes in the intestine of rats fed high-fat diets supplemented with various chromium forms. Sci Rep. 12(1):9817. doi: 10.1038/s41598-022-13328-5.
  11. Ghamry, H.I. et al. (2022). Ginseng® Alleviates Malathion-Induced Hepatorenal Injury through Modulation of the Biochemical, Antioxidant, Anti-Apoptotic, and Anti-Inflammatory Markers in Male Rats. Life (Basel). 12(5):771. doi: 10.3390/life12050771.
  12. Pérez-Soto, E. et al. (2022). High-Risk HPV with Multiple Infections Promotes CYP2E1, Lipoperoxidation and Pro-Inflammatory Cytokines in Semen of Asymptomatic Infertile Men. Antioxidants. 11(6):1051. doi: 10.3390/antiox11061051.
  13. El Okle, O.S. et al. (2022). Ornipural® Mitigates Malathion-Induced Hepato-Renal Damage in Rats via Amelioration of Oxidative Stress Biomarkers, Restoration of Antioxidant Activity, and Attenuation of Inflammatory Response. Antioxidants (Basel). 11(4):757. doi: 10.3390/antiox11040757.
  14. Maciejczyk, M. et al. (2022). α-Lipoic Acid Strengthens the Antioxidant Barrier and Reduces Oxidative, Nitrosative, and Glycative Damage, as well as Inhibits Inflammation and Apoptosis in the Hypothalamus but Not in the Cerebral Cortex of Insulin-Resistant Rats. Oxid Med Cell Longev. doi: 10.1155/2022/7450514.
  15. Maciejczyk, M. et al. (2022). Oxidation, Glycation, and Carbamylation of Salivary Biomolecules in Healthy Children, Adults, and the Elderly: Can Saliva Be Used in the Assessment of Aging? J Inflamm Res. 15:2051-2073. doi: 10.2147/JIR.S356029.
  16. Kim, Y.B. et al. (2022). Incorporation of Dietary Methyl Sulfonyl Methane into the Egg Albumens of Laying Hens. Antioxidants (Basel). 11(3):517. doi: 10.3390/antiox11030517.
  17. Ivanova, I. et al. (2022). Investigation of the HelioVital filter foil revealed protective effects against UVA1 irradiation-induced DNA damage and against UVA1-induced expression of matrixmetalloproteinases (MMP) MMP1, MMP2, MMP3 and MMP15. Photochem Photobiol Sci. doi: 10.1007/s43630-022-00177-4.
  18. Tungmunnithum, D. et al. (2022). Flavonoids from Sacred Lotus Stamen Extract Slows Chronological Aging in Yeast Model by Reducing Oxidative Stress and Maintaining Cellular Metabolism. Cells. 11(4):599. doi: 10.3390/cells11040599.
  19. Ding, J. et al. (2022). Exogenous pancreatic kininogenase protects against tacrolimus-induced renal injury by inhibiting PI3K/AKT signaling: The role of bradykinin receptors. Int Immunopharmacol. 105:108547. doi: 10.1016/j.intimp.2022.108547.
  20. Genovese, E. et al. (2022). The Response to Oxidative Damage Correlates with Driver Mutations and Clinical Outcome in Patients with Myelofibrosis. Antioxidants (Basel). 11(1):113. doi: 10.3390/antiox11010113.
  21. Gagan, J.M. et al. (2021). Constitutive transgenic alpha-Klotho overexpression enhances resilience to and recovery from murine acute lung injury. Am J Physiol Lung Cell Mol Physiol. doi: 10.1152/ajplung.00629.2020.
  22. Souza, M.A. et al. (2021). Doxycycline hyclate stimulates inducible nitric oxide synthase and arginase imbalance, potentiating inflammatory and oxidative lung damage in schistosomiasis. Biomed J. doi: 10.1016/j.bj.2021.12.007.
  23. Wu, H. et al. (2021). Trabecular meshwork mitochondrial function and oxidative stress: Clues to racial disparities of glaucoma. Ophthalmol Sci. doi: 10.1016/j.xops.2021.100107.
  24. Qi, M. et al. (2021). Inhibition mechanism of high voltage prick electrostatic field (HVPEF) on Staphylococcus aureus through ROS-mediated oxidative stress. LWT. doi: 10.1016/j.lwt.2021.112990.
  25. Zhao, J. et al. (2021). Effect of Plasma-Activated Solution Treatment on Cell Biology of Staphylococcus aureus and Quality of Fresh Lettuces. Foods. 10(12):2976. doi: 10.3390/foods10122976.
  26. Qi, M. et al. (2021). MyD88 deficiency ameliorates weight loss caused by intestinal oxidative injury in an autophagy-dependent mechanism. J Cachexia Sarcopenia Muscle. doi: 10.1002/jcsm.12858.
  27. Hu, W. et al. (2021). Topical Administration of Pterostilbene Accelerates Burn Wound Healing in Diabetes through Activation of HIF1α Signaling Pathway. Burns. doi: 10.1016/j.burns.2021.10.019.
  28. Całyniuk, Z. et al. (2021). Selected metabolic, epigenetic, nitration and redox parameters in turkeys fed diets with different levels of arginine and methionine. Ann. Anim. Sci. doi: 10.2478/aoas-2021-0069.
  29. Chan, T.K. et al. (2021). Polycyclic aromatic hydrocarbons regulate the pigmentation pathway and iinduce DNA damage responses in keratinocytes, a process driven by systemic immunity. J Dermatol Sci. doi: 10.1016/j.jdermsci.2021.09.003.
  30. Kim, H.C. et al. (2021). Glycyrrhizin ameliorating sterile inflammation induced by low-dose radiation exposure. Sci Rep. 11(1):18356. doi: 10.1038/s41598-021-97800-8.