PAK1 PBD Agarose Beads

PAK1 PBD Agarose Beads
  • Pull down only the active form of Rac or Cdc42
  • Colored for easy visualization
  • Same beads used in our Small GTPase Assays

 

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PAK1 PBD Agarose Beads
Catalog Number
STA-411
Size
400 µg
Detection
N/A
Manual/Data Sheet Download
SDS Download
Price
$510.00
Product Details

Our PAK1 PBD Agarose Beads are designed to pull down only the active form of Rac or Cdc42. These are the same beads found in our Rac Activation Assays and our Cdc42 Activation Assays.

Visible Agarose Beads. Agarose beads are colored for easy visualization, minimizing potential loss during washes and aspirations.

Recent Product Citations
  1. Crespo, G.V. et al. (2023). The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer. Mol Med. 29(1):75. doi: 10.1186/s10020-023-00678-7.
  2. Bertrand-Chapel, A. et al. (2022). SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4. Commun Biol. 5(1):1068. doi: 10.1038/s42003-022-03994-6.
  3. Bernadzki, K. M. et al. (2020). Arhgef5 Binds α-Dystrobrevin 1 and Regulates Neuromuscular Junction Integrity. Front Mol Neurosci. doi: 10.3389/fnmol.2020.00104.
  4. Speranza, L. et al. (2017). Serotonin 5-HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons. J Neurochem. doi: 10.1111/jnc.13962.
  5. Bijata, M. et al. (2016). Dystroglycan controls dendritic morphogenesis of hippocampal neurons in vitro. Front Cell Neurosci. doi:10.3389/fncel.2015.00199.
  6. Fusté, N. P. et al. (2016). Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nat Commun. doi:10.1038/ncomms11581.
  7. Alam, J. et al. (2014). N-acetylcysteine and the human serum components that inhibit bacterial invasion of gingival epithelial cells prevent experimental periodontitis in mice. J Periodontal Implant Sci. 44:266-273.
  8. Morrison, A. R. et al. (2014).  Chemokine-Coupled β2 Integrin-Induced Macrophage Rac2-Myosin IIA Interaction Regulates VEGF-A mRNA Stability and Arteriogenesis. J Exp Med. 211:1957-1968.
  9. Pothula, S. et al. (2013). Regulation of Cdc42 Expression and Signaling Is Critical for Promoting Corneal Epithelial Wound Healing. Invest. Ophthalmol. Vis. Sci. 54: 5343-5352.
  10. Sabbatini, M. E. et al. (2010). CCK Activates RhoA and Rac1 Differentially Through G-alpha-13 and G-alpha-q in Mouse Pancreatic Acini. Am. J. Physiol. Cell Physiol. 298:C592-C605.
  11. Cheng, J. et al.(2010).FSP-1 Silencing in Bone Marrow Cells Suppresses Neointima Formation in Vein Graft. Circ. Res. 110:230-240.
  12. Zhang, Q-G. et al. (2009). Estrogen Attenuates Ischemic Oxidative Damage via an Extrogen Receptor Alpha-Mediated Inhibition of NADPH Oxidase Activation. J. Neurosci. 29:13823-13836.
  13. Levy-Adam, F. et al. (2008). Heparanase Facilitates Cell Adhesion and Spreading by Clustering of Cell Surface Heparan Sulfate Proteoglycans. PLoS One 3(6):e2319.