• Quick screening tool for oxidative stress
  • User friendly protocol uses smaller reaction volumes in a 96-well format
  • Does not require glass tubes or marbles


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General FAQs about Oxidative Stress

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OxiSelect™ TBARS Assay Kit (MDA Quantitation)
Catalog Number
200 assays
Colorimetric / Fluorometric
Manual/Data Sheet Download
SDS Download
OxiSelect™ TBARS Assay Kit (MDA Quantitation)
Catalog Number
5 x 200 assays
Colorimetric / Fluorometric
Manual/Data Sheet Download
SDS Download
OxiSelect™ TBARS Assay Kit (MDA Quantitation), Trial Size
Catalog Number
20 assays
Colorimetric / Fluorometric
Manual/Data Sheet Download
SDS Download
Product Details

The TBARS (Thiobarbituric Acid Reactive Substances) assay is well-established for screening and monitoring lipid peroxidationMDA forms a 1:2 adduct with thiobarbituric acid; the MDA-TBA adduct can then be measured.

Our OxiSelect™ TBARS Assay Kit provides a much more user-friendly protocol to measure the MDA-TBA adduct. Reaction volumes are much smaller than the traditional assay, so much less sample is required. Also, reactions can be performed in standard polypropylene tubes - no glass tubes or glass marbles are required.

Important Note: MDA adducts are not stable long term. For best results test all samples immediately upon collection, or freeze them at -80ºC for up to one month. MDA may be degraded in samples that have been frozen for longer periods; in such cases more reliable results may be obtained from more stable markers of oxidative stress such as protein carbonyl, 8-OHdG or 4-HNE.

MDA-TBA Adduct

OxiSelect™ TBARS Assay Kit Standard Curve with Colorimetric Detection. The MDA standard curve can also be generated using fluorometric detection.

Recent Product Citations
  1. Magdy, Y.M. et al. (2017). Potential involvement of JNK1 repression in the hepatic effect of sitagliptin and metformin in rats subjected to high fat diet and chronic mild distress. Biomed. Pharmacother. 85:225-238.
  2. Katya, K. et al. (2016). Effects of inorganic and chelated trace mineral (Cu,Zn, Mn and Fe) premixes in marine rockfish, Sebastes schlegeli (Hilgendorf), fed diets containing phytic acid. Aquacult. Res. doi:10.1111/are.13236.
  3. Abdelsameea, A.A. et al. (2016). Liraglutide attenuates partial warm ischemia-reperfusion injury in rat livers. Naunyn Schiedebergs Arch. Pharmacol. doi:10.1007/s00210-016-1330-7.
  4. Yoon, Y.S. et al. (2016). Positive effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice. Biol. Pharm. Bulletin 37:1480-1485.
  5. Alsaadi, S.A.R.A. and Aljobory, A.M.I.S. (2016). Study the variation in biochemical parameters of post colic surgical horses which treated with chamomile flowers. Imp. J. Interdisc. Res. 2:1964-1968.
  6. Murad, H. A., et al. (2016). Oral thearubigins do not protect against acetaminophen induced hepatotoxicity in mice. Trop J Pharm Res. 15:1909-1914.
  7. Huang, E. W. et al. (2016). Endophilin-A2-mediated increase in scavenger receptor expression contributes to macrophage-derived foam cell formation. Atherosclerosis doi:10.1016/j.atherosclerosis.2016.10.009.
  8. Romero, A. et al. (2016). Oxidative stress and gene expression profiling of cell death pathways in alpha-cypermethrin-treated SH-SY5Y cells.  Arch Toxicol. doi:10.1007/s00204-016-1864-y.
  9. Thériault, P et al. (2016). High fat diet exacerbates Alzheimer’s disease-related pathology in APPswe/PS1 mice. Oncotarget. doi:10.18632/oncotarget.12179.
  10. Park, G. et al. (2016). Synergistic effects of dietary vitamin C, E and selenomethionine on growth performance, tissue mercury content and oxidative biomarkers of juvenile olive flounder, Paralichthys olivaceus (Temminck & Schlegel) toxified with the high dietary methylmercury. Anim Nutr Feed Techn. 16:155-164.
  11. Gulaboglu, M. (2016). Effects of aqueous extract of Myrtus communis L. leaves on streptozotocin-induced diabetic rats. J Res Med Den Sci. 4:214-218.
  12. Wang, L. et al. (2016). Promotion of osteointegration under diabetic conditions by tantalum coating-based surface modification on 3-dimensional printed porous titanium implants. Colloids Surf B Biointerfaces. doi:10.1016/j.colsurfb.2016.09.018.
  13. Kim, J. H. et al. (2016). Korean turmeric is effective for dyslipidemia in human intervention study. J Ethnic Food. doi:0.1016/j.jef.2016.08.006.
  14. Kim, S. et al. (2016). In vivo protective effect of phosphatidylcholine on carbon tetrachloride induced nephrotoxicityExp Toxicol Pathol. doi:10.1016/j.etp.2016.08.005.
  15. Mahmoud, A. M. et al. (2016).  A novel role for small molecule glycomimetics in the protection against lipid-induced endothelial dysfunction:Involvement of Akt/eNOS and Nrf2/ARE signaling. Biochim Biophys Acta.doi:10.1016/j.bbagen.2016.08.013.
  16. Fraczek, M. et al. (2016). The effect of bacteriospermia and leukocytospermia on conventional and nonconventional semen parameters in healthy young normozoospermic males. J Reprod Immunol. 118:18-27.
  17. Martino, N. A. et al. (2016). Supplementation with nanomolar concentrations of verbascoside during in vitro maturation improves embryo development by protecting the oocyte against oxidative stress: a large animal model study. Reprod Toxicol. doi:10.1016/j.reprotox.2016.08.004.
  18. Shaik-Dasthagirisaheb, Y. B. et al. (2016). Signaling events in pathogen-induced macrophage foam cell formation. Pathog Dis.doi:10.1093/femspd/ftw074.
  19. Gupta, R. et al. (2016). Coupling of gel-based 2-DE and 1-DE shotgun proteomics approaches to dig deep into the leaf senescence proteome of Glycine max. J Proteomics. 148:65-74.
  20. Liu, W. et al. (2016). Selenium nanoparticles incorporated into titania nanotubes inhibit bacterial growth and macrophage proliferation. Nanoscale. 8:15783-15794.
  21. Hong, J. et al. (2016). The optimum dietary docosahexaenoic acid level based on growth and non-specific immune responses in juvenile rock bream, Oplegnathus fasciatus. Aquacult Res. doi:10.1111/are.13167.
  22. Saleh, D. O. & Mansour, D. F. (2016). Ovario-protective effects of genistein against cyclophosphamide toxicity in rats: Role of anti-müllerian hormone and oestradiol. Eur J Pharmacol. doi:10.1016/j.ejphar.2016.07.026.
  23. Bacchi, S. et al. (2016). Cocaine effects on generation of reactive oxygen species and DNA damage: formation of 8-hydroxydeoxyguanosine in active abusers. Int J Pharmacol Toxicol. doi:10.14419/ijpt.v4i2.5970.
  24. Dhall, S. et al. (2016). Tobacco toxins deposited on surfaces (third hand smoke) impair wound healing. Clin Sci. doi:10.1042/CS20160236.
  25. Kosutova, P. et al. (2016). Effects of S-nitroso-N-acetyl-penicillamine (SNAP) on inflammation, lung tissue apoptosis and iNOS activity in a rabbit model of acute lung injury. Adv Exp Med Biol. doi:10.1007/5584_2016_34.
  26. Saben, J. L. et al. (2016). Maternal metabolic syndrome programs mitochondrial dysfunction via germline changes across three generations. Cell Rep. doi:10.1016/j.celrep.2016.05.065.
  27. Abd-ElSalam, H. H. et al. (2016). Correlation of in vivo and in vitro assay results for assessment of free radical scavenging activity of green tea nutraceuticals. J Food Sci. doi:10.1111/1750-3841.13362.
  28. Murad, H. A. et al. (2016). Mentha longifolia protects against acetic-acid induced colitis in rats. J Ethnopharmacol. doi:10.1016/j.jep.2016.06.016.
  29. Kim, B. et al. (2016). Major benzophenone concentrations and influence of food consumption among the general population in Korea, and the association with oxidative stress biomarker. Sci Total Environ. 565:649-655.
  30. Tafelmeier, M.. et al. (2016). Mildly oxidized HDL decrease agonist-induced platelet aggregation and release of pro-coagulant platelet extracellular vesicles. J Steroid Biochem Mol Bioldoi:10.1016/j.jsbmb.2016.05.003.
  31. Nirajan, S. et al. (2016). Glutamine inhibits CCl 4 induced liver fibrosis in mice and TGF-β1 mediated epithelial-mesenchymal transition in mouse hepatocytes. Food Chem Toxicol. doi:10.1016/j.fct.2016.04.024.
  32. Sudini, K. et al. (2016). A randomized controlled trial of the effect of broccoli sprouts on antioxidant gene expression and airway inflammation in asthmatics.J Allergy Clin Immunol Pract. doi:10.1016/j.jaip.2016.03.012.
  33. El Okda, E. A. et al. (2016). Switching to instant black coffee modulates sodium selenite-induced cataract in rats. Ger Med Sci. doi:10.3205/000232.
  34. Ngcobo, M. et al. (2016). Antimutagenic and antioxidant effects of a South African traditional formulation used as an immune booster. S Afr J Sci. doi:10.17159/sajs.2016/20150152.
  35. Gallego-Villar, L. et al. (2016). In vivo evidence of mitochondrial dysfunction and altered redox homeostasis in a genetic mouse model of propionic acidemia: Implications for the pathophysiology of this disorder. Free Radic Biol Med. doi:10.1016/j.freeradbiomed.2016.04.007.
  36. Romero, A. et al. (2016). Fipronil sulfone induced higher cytotoxicity than fipronil in SH-SY5Y cells: Protection by antioxidants. Toxicol Lett. doi:10.1016/j.toxlet.2016.04.005.
  37. Nishikido, T. et al. (2016). Deletion of apoptosis inhibitor of macrophage (AIM)/CD5L attenuates the inflammatory response and infarct size in acute myocardial infarction. J Am Heart Assoc. doi:10.1161/JAHA.115.002863.
  38. Pandurangan, M. & Kim, D. H. (2016). Therapeutic potential of cyanobacteria against streptozotocin-induced diabetic rats. 3 Biotech. doi:10.1007/s13205-016-0411-0.
  39. Kara, M. et al. (2016). Evaluation of the protective effects of hesperetin against cisplatin-induced ototoxicity in a rat animal model. Int J Pediatr Otorhinolaryngol. 85:12-18.
  40. Mikolka, P. et al. (2016). Effects of surfactant/budesonide therapy on oxidative modifications in the lung in experimental meconium-induced lung injury. J Physiol Pharmacol. 67:57-65.
  41. Li, L.F. et al. (2016). Inhibition of Src and FoxO1 signaling by induced pluripotent stem cell therapy attenuates hyperoxia-augmented ventilator-induced diaphragm dysfunction. Transl Res. doi:10.1016/j.trsl.2016.03.011.
  42. Katya, K. et al. (2016). Efficacy of inorganic and chelated trace minerals (Cu, Zn and Mn) premix sources in Pacific white shrimp, Litopenaeus vannamei (Boone) fed plant protein based diets. Aquaculture. doi:10.1016/j.aquaculture.2016.03.033.
  43. Canayakin, D. et al. (2016). Paracetamol-induced nephrotoxicity and oxidative stress in rats: the protective role of Nigella sativa. Pharm Biol. doi:10.3109/13880209.2016.1145701.
  44. Adhami, N. et al. (2016). A health threat to bystanders living in the homes of smokers: How smoke toxins deposited on surfaces can cause insulin resistance. PLoS One. 11:e0149510.
  45. Gostimskaya, I. & Grant. C. M. (2016). Yeast mitochondrial glutathione is an essential antioxidant with mitochondrial thioredoxin providing a back-up system. Free Radic Biol Med. doi:10.1016/j.freeradbiomed.2016.02.015.
  46. Fang, Y. et al. (2016). Protective effect of alpha-mangostin against oxidative stress induced-retinal cell death. Sci Rep. doi:10.1038/srep21018.
  47. Woo, J. E. et al. (2016). Soy products fermented with sprouted garlic have increased neuroprotective activities and restore cognitive functions. Food Sci Biotechnol. doi:10.1007/s10068-016-0043-5.
  48. Kim, H. J. et al. (2016). Protective effect of pterostilbene on testicular ischemia/reperfusion injury in rats. J Pediatr Surg. doi:10.1016/j.jpedsurg.2016.01.009.
  49. Lee, J. H. et al. (2016). Effect of non-thermal air atmospheric pressure plasma jet treatment on gingival wound healing. J Phys D Appl Phys. 49:075402.
  50. Zhang, L. et al. (2015). Melamine nephrotoxicity is mediated by hyperuricemia. Biomed Environ Sci. 28:904-912.
  51. Zaid, S. S. M. et al. (2015). Tualang honey protects against BPA-induced morphological abnormalities and disruption of ERα, ERβ, and C3 mRNA and protein expressions in the uterus of rats. Evid Based Complementary Altern Med. 202874.
  52. Mohamed, R. A. et al. (2015). Role of adenosine A 2A receptor in cerebral ischemia reperfusion injury: Signaling to phosphorylated extracellular signal regulated protein kinase (pERK1/2). Neuroscience. doi:10.1016/j.neuroscience.2015.11.059.
  53. Dugbartey, G. J. et al. (2015). Dopamine treatment attenuates acute kidney injury in a rat model of deep hypothermia and rewarming–The role of renal H2S-producing enzymes. Eur J Pharmacol. 769:225-33.
  54. Pettersen, K. et al. (2015). DHA-induced stress response in human colon cancer cells-focus on oxidative stress and autophagy. Free Radic Biol Med. 90:158-172.
  55. Songstad, N. T. et al. (2015). Effects of high intensity interval training on pregnant rats, and the placenta, heart and liver of their fetuses. PLoS One. 10:e0143095.
  56. Shahkar, E. et al. (2015). Evaluation of the optimum dietary arachidonic acid level and its essentiality based on growth and non-specific immune responses in Japanese eel, Anguilla japonica. Aquaculture. 452:209-216.
  57. Brand, R. M. et al. (2015). Skin immunization obviates alcohol-related immune dysfunction. Biomolecules. 5:3009-3028.
  58. Yiu, W. H. et al. (2015). Kallistatin protects against diabetic nephropathy in db/db mice by suppressing AGE-RAGE-induced oxidative stress. Kidney Int. doi:10.1038/ki.2015.331.
  59. Afify, H. et al. (2015). Molecular mechanisms of the modulatory effect of vitamin E on tacrolimus (FK506)-induced renal injury in rats. Br J Pharm Res. 9:1-9.
  60. Li, S. et al. (2015). Impact of natural organic matter on particle behavior and phototoxicity of titanium dioxide nanoparticles. Sci Total Environ. 542:324-333.
  61. Zheng, H. M. et al. (2015). Centella asiatica leaf extract protects against indomethacin-induced gastric mucosal injury in rats. J Med Food. doi:10.1089/jmf.2015.3464.
  62. Palipoch, S. et al. (2015). Heme oxygenase-1 alleviates alcoholic liver steatosis: histopathological study. J Toxicol Pathol. doi:10.1293/tox.2015-0035.
  63. Dhall, S. et al. (2015). Release of insulin from PLGA–alginate dressing stimulates regenerative healing of burn wounds in rats. Clin Sci (Lond). 129:1115-1129.
  64. Galougahi, K. K. et al. (2015). β3-Adrenoceptor activation relieves oxidative inhibition of the cardiac Na+-K+ pump in hyperglycemia induced by insulin receptor blockade. Am J Physiol Cell Physiol. 309:C286-C295.
  65. Dal, S. et al. (2015). Oxidative stress status and liver tissue defenses in diabetic rats during intensive subcutaneous insulin therapy. Exp Biol Med. doi:10.1177/1535370215603837.
  66. Lee, J. Y. et al. (2015). Effects of non-thermal plasma on the electrical properties of an erythrocyte membrane. Appl Phys Lett107: 113701. 
  67. Sun, Y. et al. (2015). Impacts of low level aflatoxin in feed and the use of yeast cell wall based feed additive on growth and health of nursery pigs 1. Anim Nutr.  doi:10.1016/j.aninu.2015.08.012.
  68. Rangel-Huerta, O. D. et al. (2015). Normal or high polyphenol concentration in orange juice affects antioxidant activity, blood pressure, and body weight in obese or overweight adults. J Nutr.  145:1808-1816.
  69. Sosa, R. A. et al. (2015). IFN-γ ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation. Proc Natl Acad Sci U S A. 112:E5038-E5047.
  70. Shin, S. H. et al. (2015). Oxidative stress induced by low-dose doxorubicin promotes the invasiveness of osteosarcoma cell line U2OS in vitro. Tumour Biol. doi:10.1007/s13277-015-3702-x.
  71. Gupt, A. M. et al. (2015). Effect of moderate aerobic exercise training on pulmonary functions and its correlation with the antioxidant status.Natl J Med Res.5:136-139.
  72. Kumagai, Y. et al. (2015). Anti-glycation effects of pomegranate (Punica granatum L.) fruit extract and its components in vivo and in vitro. J Agric Food Chem. doi:10.1021/acs.jafc.5b02766.
  73. Silva, J. P. et al. (2015). Improved burn wound healing by the antimicrobial peptide LLKKK18 released from conjugates with dextrin embedded in a carbopol gel. Acta Biomater.  doi:10.1016/j.actbio.2015.07.043.
  74. Eldin, E. E. et al. (2015). The role of antiepileptic drugs in free radicals generation and antioxidant levels in epileptic patients.  Int J Neurosci. doi:10.3109/00207454.2014.994207.
  75. Shigeta, T. et al. (2015). Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats. Transplantation.doi:10.1097/TP.0000000000000510.
  76. Polat, M. et al. (2015). Assessing the effect of leptin on liver damage in case of hepatic injury associated with paracetamol poisoning. Gastroenterol Res Pract. 501:357360.
  77. Mikail, M. A. et al. (2015). Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities. Eur J Nutr. doi:10.1007/s00394-015-0961-7.
  78. Guven, M. et al. (2015). The neuroprotective effect of kefir on spinal cord ischemia/reperfusion injury in rats. J Korean Neurosurg Soc. 57:335-341.
  79. Yang, M. et al. (2015). The liver X receptor agonist TO901317 protects mice against cisplatin-induced kidney injury. Exp Biol Med (Maywood). doi:10.1177/1535370215589906.
  80. Gupt, A. M. et al. (2015). Effect of moderate aerobic exercise training on autonomic functions and its correlation with the antioxidant status. Indian J Physiol Pharmacol. 59:162-169.
  81. Dal, S. et al. (2015). Portal or subcutaneous insulin infusion: efficacy and impact on liver inflammation. Fundam Clin Pharmacol. doi: 10.1111/fcp.12129.
  82. Calzia, D. et al. (2015). Effect of polyphenolic phytochemicals on ectopic oxidative phosphorylation in rod outer segments. Br J Pharmacol.  doi: 10.1111/bph.13173. 
  83. Qin, J. et al. (2015). Fluorofenidone attenuates oxidative stress and renal fibrosis in obstructive nephropathy via blocking NOX2 (gp91phox) expression and inhibiting ERK/MAPK signaling pathway. Kidney Blood Press Res. 40:89-99.
  84. Wu, Y. P. et al. (2015). Cedrus deodara pine needle as a potential source of natural antioxidants: Bioactive constituents and antioxidant activities. J Funct Foods. 14:605-612.
  85. Yener, A. U. et al. (2015). Effects of kefir on ischemia-reperfusion injury. Eur Rev Med Pharmacol Sci. 19:887-896.
  86. Abdelsalam, R. M. & Safar, M. M. (2015). Neuroprotective effects of vildagliptin in rat rotenone Parkinson's disease model: role of RAGE‐NFκB and Nrf2‐antioxidant signaling pathways. J Neurochem. doi: 10.1111/jnc.13087.
  87. Guzmán, M. A. et al. (2015). Glycemic control and oxidative stress markers and their relationship with the thioredoxin interacting protein (TXNIP) gene in type 2 diabetic patients. Nutr Hosp. 31:1129-1133.
  88. Banday, A. A. & Lokhandwala, M. F. (2015). Transcriptional regulation of renal dopamine D1 receptor function during oxidative stress. Hypertension. doi:10.1161/HYPERTENSIONAHA.115.05255.
  89. Chung, W. S. et al. (2015). Hepatoprotective effect of Lentinus edodes mycelia fermented formulation against alcoholic liver injury in rats. J Food Biochem. doi: 10.1111/jfbc.12124
  90. Wilson, G. J. et al. (2015). GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment. Am J Physiol Endocrinol Metab. 308:E283-E293.
  91. Mika, M. et al. (2015). Anti-atherosclerotic activity of catechins depends on their stereoisomerism. Atherosclerosis. doi:10.1016/j.atherosclerosis.2015.02.026.
  92. Romero, A. et al. (2015). Evidence for dose-additive effects of a type II pyrethroid mixture. In vitro assessment. Environ Res. 138:58-66.
  93. Mora, M. et al. (2015). Minocycline increases the activity of superoxide dismutase and reduces the concentration of nitric oxide, hydrogen peroxide and mitochondrial malondialdehyde in manganese treated Drosophila melanogaster. Neurochem Res. 39:1270-1278.
  94. Niska, K. et al. (2015). Titanium dioxide nanoparticles enhance production of superoxide anion and alter the antioxidant system in human osteoblast cells. Int J Nanomedicine. 10:1095-1097.
  95. Kim, B. R. et al. (2015). Suppression of 7, 12-Dimethylbenz (a) anthracene-induced mammary tumorigenesis by glyceollins. Mol Nutr Food Res. doi: 10.1002/mnfr.201400726. 
  96. Choi, J. W. et al. (2015). Protective effect of Porphyra yezoensis glycoprotein on D-galactosamine‑induced cytotoxicity in Hepa 1c1c7 cells.Mol Med Rep. doi:10.3892/mmr.2015.3244.
  97. Jangiam, W. et al. (2015). Induction of chronic oxidative stress, chronic inflammation and aberrant patterns of DNA methylation in the liver of titanium-exposed CBA/CaJ mice. Int J Radiat Biol.  doi:10.3109/09553002.2015.1001882.
  98. Schwartz, J. L. et al. (2015). Inhibition of EGFR suppresses ethyl alcohol and tobacco cell effects on growth of human oral keratinocytes and human papillomavirus 16 entry as a function of furin. Journal of Cancer Therapy. 6:90-108.
  99. Shahkar, E. et al. (2015). Effects of dietary vitamin C levels on tissue ascorbic acid concentration, hematology, non-specific immune response and gonad histology in broodstock Japanese eel, Anguilla japonica. Aquaculture. 438:115-121.
  100. Nassar, N. N. et al. (2015). Saxagliptin: a novel antiparkinsonian approach. Neuropharmacology. 89:308-317.
  101. Li, X. et al. (2015). Osseointegration of chitosan coated porous titanium alloy implant by reactive oxygen species-mediated activation of the PI3K/AKT pathway under diabetic conditions. Biomaterials. 36:44-54.
  102. Li, R. X. et al. (2015). BMP7 reduces inflammation and oxidative stress in diabetic tubulopathy.Clin Sci (Lond). 128:269-280.
  103. Ichikawa, D. et al. (2015). Human liver-type fatty acid-binding protein protects against tubulointerstitial injury in aldosterone-induced renal injury. Am J Physiol Renal Physiol. 308:F114-F121.
  104. Wang, L. et al. (2015). Insulin improves osteogenesis of titanium implants under diabetic conditions by inhibiting reactive oxygen species overproduction via the PI3K-Akt pathway.Biochimie. 108:85-93.
  105. Kim, D. H. et al. (2014). Effect of a neutrophil elastase inhibitor on ventilator-induced lung injury in rats.J Thorac Dis. 6:1681.
  106. Antošová, M. et al. (2015). The influence of L-NAME on iNOS expression and markers of oxidative stress in allergen-induced airway hyperreactivity.Adv Exp Med Biol.838:1-10.
  107. Antognelli, C. et al. (2014). Glyoxalase I inhibition induces apoptosis in irradiated MCF-7 cells via a novel mechanism involving Hsp27, p53 and NF-κB. Br J Cancer. 111:395-406.
  108. Park, D. H. et al. (2014). Association of plasma malondialdehyde with ARMS2 genetic variants and phenotypes in polypoidal choroidal vasculopathy and age-related macular degeneration. Retina.  34:1167-1176.
  109. El Morsy, E. M. et al. (2014). Attenuation of renal ischemia/reperfusion injury by açaí extract preconditioning in a rat model. Life Sci. 123:35-42.
  110. Fraczek, M. et al. (2014). Fertilizing potential of ejaculated human spermatozoa during in vitro semen bacterial infection. Fertil Steril. 102:711-719.
  111. Dhall, S. et al. (2014). A novel model of chronic wounds: importance of redox imbalance and biofilm-forming bacteria for establishment of chronicity. PLoS One. 9:e109848.
  112. Cho, E. J. et al. (2014). Tauroursodeoxycholic acid attenuates progression of steatohepatitis in mice fed a methionine–choline-deficient diet.  Dig Dis Sci. 59:1461-1474.
  113. de Sousa, M. C. et al. (2014). Antioxidants and biomarkers of oxidative damage in the saliva of patients with Down's syndrome. Arch Oral Biol. 60:600-605.
  114. Hong, Y. A. et al. (2014). Delayed treatment with oleanolic acid attenuates tubulointerstitial fibrosis in chronic cyclosporine nephropathy through Nrf2/HO-1 signaling. J Transl Med. 12:50.
  115. Alkhotani, A. et al. (2014). Evaluation of neonatal jaundice in the Makkah region. Sci Rep.  4:4802.
  116. Zhang, Y. et al. (2014). Gene expression profile analysis of rat cerebellum under acute alcohol intoxication. Gene. 557:188-194.
  117. Lee, D. S. et al. (2014). Ameliorating effects of HX106N, a water-soluble botanical formulation, on Abeta25-35-induced memory impairment and oxidative stress in mice. Biol Pharm Bull.  37:954-60.
  118. Kim, J. H. et al. (2014). Chronic vitamin C insufficiency aggravated thioacetamide-induced liver fibrosis in gulo-knockout mice. Free Radic Biol Med. 67:81-90.
  119. Haggag, B. S. et al. (2014). Lamotrigine decreased hippocampal damage and improved vascular risk markers in a rat model of pentylenetetrazole induced kindling seizure.Korean J Physiol Pharmacol. 18:269-278.
  120. Inkielewicz-Stepniak, I. et al. (2014). Pharmacological and toxicological effects of co-exposure of human gingival fibroblasts to silver nanoparticles and sodium fluoride. Int J Nanomedicine.  9:1677-1687.
  121. Andrews Guzman, M., and Arredondo Olguín, M. (2014). Association between ferritin, high sensitivity c-reactive protein (hsCRP) and relative abundance of Hepcidin mRNA with the risk of type 2 diabetes in obese subjects. Nutr Hosp.30:577-584.
  122. Mikešová, K. et al. (2014). Effect of evening primrose oil on biochemical parameters of thoroughbred horses under maximal training conditions. Czech J Anim Sci. 59:488-493.
  123. Yoon, Y. S. et al. (2014). Positive Effects of hydrogen water on 2, 4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice. Biol Pharm Bull. 37:1480-1485.
  124. Seif, A. A. & Abdelwahed, D. M.  (2014). Vitamin D ameliorates hepatic ischemic/reperfusion injury in rats. J Physiol Biochem. 70:659-666.
  125. Lepper-Blilie, A. N. et al. (2014). Effectiveness of oxygen barrier oven bags in low temperature cooking on reduction of warmed-over flavor in beef roasts. Meat Sci. 96:1361-1364.
  126. Mao, J. et al. (2014). Apolipoprotein AI expression suppresses COX-2 expression by reducing reactive oxygen species in hepatocytes. Biochem Biophys Res Commun. 454:359-363.
  127. Mauderly, J. L. et al. (2014). The National Environmental Respiratory Center (NERC) experiment in multi-pollutant air quality health research: IV. Vascular effects of repeated inhalation exposure to a mixture of five inorganic gases. Inhal Toxicol. 26:691-696.
  128. Hamilton, J. P. et al. (2014). Effects of vitamin D3 stimulation of thioredoxin‐interacting protein in hepatocellular carcinoma. Hepatol Res. 44:1357-1366.
  129. Weaver, A. C. et al. (2014). Protective effect of two yeast based feed additives on pigs chronically exposed to deoxynivalenol and zearalenone. Toxins (Basel). 6:3336-3353.
  130. Kim, W. K. et al. (2014). Tissue-specific antioxidant responses in pale chub (Zacco platypus) exposed to copper and benzo[a]pyrene. Bull Environ Contam Toxicol. 92:540-545.
  131. Medina-Leendertz, S. et al. (2014). Longterm melatonin administration alleviates paraquat mediated oxidative stress in Drosophila melanogaster. Invest Clin. 55:352-364.
  132. Yang, T. et al. (2014). Anti-apoptotic and anti-oxidative roles of quercetin after traumatic brain injury. Cell Mol Neurobiol. 34:797-804.
  133. Wei, W. et al (2014). Effect of fluorosis on liver cells of VC deficient and wild type mice. Scientific World Journal. doi:10.1155/2014/287464.
  134. Palipoch, S. et al. (2014). Hepatoprotective effect of curcumin and alpha-tocopherol against cisplatin-induced oxidative stress. BMC Complement Altern Med. 14:111.
  135. Shen, Y. B. et al. (2014). Effect of Feed Grade l-Methionine on Growth Performance and Gut Health in Nursery Pigs Compared with Conventional dl-Methionine. J Anim Sci. 92:5530-5539.
  136. Weaver, A. C. et al. (2014).  Efficacy of Dietary Spray Dried Plasma Protein to Mitigate the Negative Effects on Performance of Pigs Fed Diets with Corn Naturally Contaminated with Multiple Mycotoxins. J Anim Sci. 9:3878-3886.
  137. Mohammad, M. K. et al. (2014).  Watermelon (Citrullus lanatus (Thunb.) Matsum. and Nakai) Juice Modulates Oxidative Damage Induced by Low Dose X-ray in Mice. Biomed Res Int. 2014:512834.
  138. Mohamed, M. I. et al. (2014).  Induction of Oxidative Stress Following Low Dose Ionizing Radiation in ICR Mice. World J Med Sci. 10:198-203.
  139. Chang, Q. et al. (2014). Cytochrome P450 2C epoxygenases mediate photochemical stress-induced death of photoreceptors. J. Biol. Chem. 289:8337-8352.
  140. Gomez-Marcos, M.A. et al. (2014). Relationship between target organ damage and blood pressure, retinal vessel calibre, oxidative stress and polymorphisms in VAV-2 and VAV-3 genes in patients with hypertension: a case-control study protocol (LOD-Hipertension). BMJ Open 4:e005112.
  141. Palipoch, S. et al. (2013). Amelioration of cisplatin-induced nephrotoxicity in rats by curcumin and α-tocopherol. Tropical Journal of Pharmaceutical Research. 12:973-979.
  142. Mahran, Y. et al. (2013). Insights into the Protective Mechanisms of Tamoxifen in Radiotherapy-Induced Ovarian Follicular Loss: Impact on Insulin-Like Growth Factor 1. Endocrinology. 154:3888-3899.
  143. Song, J. et al. (2013). Nicotinamide Phosphoribosyltransferase Is Required for the Calorie Restriction–Mediated Improvements in Oxidative Stress, Mitochondrial Biogenesis, and Metabolic Adaptation. J. Gerontol A Biol Sci Med Sci. 10.1093/gerona/glt122.
  144. Fu, L. et al. (2012). Ethyl Pyruvate Reduces Ventilation-Induced Neutrophil Infiltration and Oxidative Stress. J. Lipid Res. 53: 1080-1092.
  145. Brindeiro, C.M. et al.(2012).Tempol Prevents Altered K+ Channel Regulation of Afferent Arteriolar Tone in Diabetic Rat Kidney. Hypertension.59:657 - 664. 
  146. Mühlfeld, C. et al. (2011). Cancer induces cardiomyocyte remodeling and hypoinnervation in the left ventricle of the mouse heart.PLoS One6:e20424.
  147. Joshi, S. G. et al. (2011). Nonthermal Dielectric-Barrier Discharge Plasma-Induced Inactivation Involves Oxidative DNA Damage and Memebrane Lipid Peroxidation in Escherichia coli. Antimicrob. Agents Chemother. 55:1053-1062.
  148. Kasaikina, M.V. et al. (2011). Roles of the 15-kDa Selenoprotein (Sep15) in Redox Homeostasis and Cataract Development Revealed by the Analysis of Sep 15 Knockout Mice. J. Biol. Chem. 286:33203-33212.
  149. Fedeles, B. I. et al. (2011). Chemical Genetics Analysis of an Aniline Mustard Anticancer Agent Reveals Complex I of the Electron Transport Chain as a Target. J. Biol. Chem. 286:33910-33920.
  150. Kwon, H. et al. (2010). Vitamin D3 Upregulated Protein 1 Suppresses TNF-α–Induced NF- κB Activation in Hepatocarcinogenesis. J. Immunol. 185:3980-3989.
  151. Wojciechowski, P. et al. (2010). Resveratrol Arrests and Regresses the Development of Pressure Overload- but Not Volume Overload-Induced Cardiac Hypertrophy in Rats. J. Nutr. 140:962-968.
  152. Song, Y.R. et al. (2010). Activation of Hypoxia-Inducible Factor Attenuates Renal Injury in Rat Remnant Kidney. Nephrol. Dial. Transplant. 25:77-85.
  153. Fomenko, D.E. et al. (2008). Methionine-R-sulfoxide reductase 1 (MsrB1) Knockout Mice: Roles of MsrB1 in Redox Regulation and Identification of a Novel Selenoprotein Form. J. Biol. Chem. 284:5986-5993.
  154. Fujita, K. et al. (2008). Effectiveness of Antiplatelet Drugs Against Experimental Non-Alcoholic Fatty Liver Disease. Gut 57:1583-1591.