Lipoprotein Metabolism

Lipoproteins are important protein-lipid assemblies that are responsible for the transport of fats to different parts of the body via the bloodstream. The five major groups of lipoproteins are very low-density lipoprotein (VLDL), low-density lipoprotein (LDL), intermediate-density lipoprotein (IDL), high-density lipoprotein (HDL), and chylomicrons. LDL and HDL are of particular interest due to their impact on human health.

Lipoproteins are composed of lipids and proteins which are held together by noncovalent forces. There is an outer layer of phospholipids, unesterified cholesterol, and proteins, with a core of neutral lipids predominately cholesteryl esters and triacylglycerols (TAG). Apolipoproteins are the proteins that, along with other amphipathic molecules, surround the lipids to make up the lipoproteins. This association allows lipoproteins to be carried through water-based circulation, specifically blood and lymph.

Our assays include simple, convenient tests to measure levels of cholesterols, triglycerides, and phospholipids. We also offer a variety of ELISA kits that allow you to study specific apolipoproteins, lipoprotein receptors, and various serum proteins. In addition to assay kits, we also provide a variety of lipoproteins and apolipoproteins as well as antibodies to these transporters.